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Sexually transmitted diseases

Section edited by Stefan Baral & Joseph Tucker

This section aims to publish studies looking at all aspects of of the prevention, diagnosis and management of sexually transmitted diseases in humans, as well as related molecular genetics, pathophysiology, and epidemiology. HIV and HIV-associated infections are considered in a separate section.

Page 1 of 6

  1. Content type: Case report

    Despite effective antiretroviral therapy developed over the last decade, HIV infection remains a major worldwide public health problem. Recently, a promising preventive treatment has been made available for HI...

    Authors: Elise K. Van Obberghen, Delphine Viard, Alain Lafeuillade, Alexandre Civiletti, Fanny Rocher and Milou-Daniel Drici

    Citation: BMC Infectious Diseases 2019 19:601

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  2. Content type: Case report

    In Japan and other countries, the number of patients with syphilis is increasing year by year. Recently, the cases of the pulmonary involvement in patients with secondary syphilis have been reported. However, ...

    Authors: Shinji Futami, Takayuki Takimoto, Futoshi Nakagami, Shingo Satoh, Masanari Hamaguchi, Muneyoshi Kuroyama, Kotaro Miyake, Shohei Koyama, Kota Iwahori, Haruhiko Hirata, Izumi Nagatomo, Yoshito Takeda, Hiroshi Kida and Atsushi Kumanogoh

    Citation: BMC Infectious Diseases 2019 19:598

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  3. Content type: Research article

    Human papillomavirus (HPV) causes cancers in men, including penile, anal, and oropharyngeal cancers. This cross-sectional study aimed to investigate the prevalence, the genotypes, and the risk factors of HPV i...

    Authors: Hai Ha Long Le, Xiuqiong Bi, Azumi Ishizaki, Hung Van Le, Trung Vu Nguyen and Hiroshi Ichimura

    Citation: BMC Infectious Diseases 2019 19:578

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  4. Content type: Research article

    In a context of increasing use of Nucleic Acid Amplification Test, diagnoses of Neisseria gonorrhoeae and Chlamydia trachomatis infections among men increased in Europe and USA since 2007. We aimed to describe tr...

    Authors: Louise Rossignol, Laurianne Feuillepain, Ndeindo Ndeikoundam Ngangro, Cécile Souty, Nelly Fournet, Yann Le Strat, Noémie Baroux, Thomas Hanslik, Florence Lot and Thierry Blanchon

    Citation: BMC Infectious Diseases 2019 19:561

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  5. Content type: Research article

    Human papillomavirus (HPV) is the most widespread sexually transmitted infection worldwide. It causes several health consequences, in particular accounting for the majority of cervical cancer cases in women. I...

    Authors: Samik Datta, Joshua Pink, Graham F. Medley, Stavros Petrou, Sophie Staniszewska, Martin Underwood, Pam Sonnenberg and Matt J. Keeling

    Citation: BMC Infectious Diseases 2019 19:552

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  6. Content type: Research article

    Demographic characteristic surveillance of transfusion-transmitted infections (TTIs) among blood donors is crucial to formulating control strategies and preventing TTIs. This study aimed to investigate the dem...

    Authors: Le Chang, Junpeng Zhao, Fei Guo, Huimin Ji, Lu Zhang, Xinyi Jiang and Lunan Wang

    Citation: BMC Infectious Diseases 2019 19:514

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  7. Content type: Research article

    High-risk population of blood donation increases the prevalence of transmit blood-borne diseases and harm the blood safety. Syphilis accounts for approximately 10% of commonly sexually transmitted diseases. Th...

    Authors: Shuangli Liu, Liping Luo, Guangxiang Xi, Like Wan, Li Zhong, Xue Chen, Tianxiang Gong, Shuping Li, Yi He and Na Li

    Citation: BMC Infectious Diseases 2019 19:509

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  8. Content type: Research article

    Understanding the underlying epidemiology that shapes Neisseria gonorrhoeae (GC), and Chlamydia trachomatis (CT) infections can contribute to data driven policies directed towards curbing the proliferation of the...

    Authors: Helena Dela, Naiki Attram, Eric Behene, Selassie Kumordjie, Kwasi Kennedy Addo, Edward Owusu Nyarko, Nicholas N. A. Kyei, John Nii Ayite Carroll, Cynthia Kwakye, Christopher Anthony Duplessis, Nehkonti Adams, Eric Garges and Andrew Gordon Letizia

    Citation: BMC Infectious Diseases 2019 19:425

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  9. Content type: Research article

    Herpes simplex virus type-2 (HSV-2) infection is the main cause of genital ulcer disease and increases the risk of HIV acquisition. Little information is available regards the epidemiological characteristics o...

    Authors: Pengcheng Huai, Furong Li, Zhen Li, Lele Sun, Xi’an Fu, Qing Pan, Gongqi Yu, Zemin Chai, Tongsheng Chu, Zihao Mi, Fangfang Bao, Honglei Wang, Bingni Zhou, Chuan Wang, Yonghu Sun, Guiye Niu…

    Citation: BMC Infectious Diseases 2019 19:382

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  10. Content type: Research article

    Syphilis is a sexually transmitted infection caused by the bacterium Treponema pallidum. The disease affects all ages and both sexes but more prevalent among the sexually active age group of 15–49 years. The purp...

    Authors: Martin Banong-le, Samuel Kwabena Ofosu and Francis Anto

    Citation: BMC Infectious Diseases 2019 19:360

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  11. Content type: Research article

    Cervical cancer is caused by oncogenic human papillomaviruses (HPV) and is one of the most common malignancies in women living in sub-Saharan Africa. Women infected with the human immunodeficiency virus (HIV) ...

    Authors: A. Ermel, P. Tonui, M. Titus, Y. Tong, N. Wong, J. Ong’echa, K. Muthoka, S. Kiptoo, A. Moormann, J. Hogan, A. Mwangi, S. Cu-Uvin, P. J. Loehrer, O. Orang’o and D. Brown

    Citation: BMC Infectious Diseases 2019 19:352

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  12. Content type: Research article

    Virological treatment failure is a problem that a Human Immune Virus patient faces after starting treatment due to different factors. However, there were few studies done on the predictors of virological treat...

    Authors: Mohammed Ahmed, Hailu Merga and Habtemu Jarso

    Citation: BMC Infectious Diseases 2019 19:305

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  13. Content type: Research article

    Syphilis is responsible for a substantial burden of preventable adverse outcomes in pregnancy. The purpose of this study was to compare the frequency of adverse pregnancy outcomes among syphilis-seropositive w...

    Authors: Huihui Liu, Niannian Chen, Jia Yu, Weiming Tang, Jianrong He, Huiyun Xiao, Suifang Lin, Fang Hu, Qiong Feng, Joseph D. Tucker, Huimin Xia and Xiu Qiu

    Citation: BMC Infectious Diseases 2019 19:292

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  14. Content type: Research article

    Confidence in any diagnostic and antimicrobial susceptibility testing data is provided by appropriate and regular quality assurance (QA) procedures. In Europe, the European Gonococcal Antimicrobial Susceptibil...

    Authors: Michelle J. Cole, Nerteley Quaye, Susanne Jacobsson, Michaela Day, Elizabeth Fagan, Catherine Ison, Rachel Pitt, Shila Seaton, Neil Woodford, Angelika Stary, Sonja Pleininger, Tania Crucitti, Blaženka Hunjak, Panayiota Maikanti, Steen Hoffmann, Jelena Viktorova…

    Citation: BMC Infectious Diseases 2019 19:281

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  15. Content type: Research article

    Across diverse regions globally, sex workers continue to face a disproportionate burden of HIV and other sexually transmitted and blood borne infections (STBBIs). Evidence suggests that behavioural and biomedi...

    Authors: Elena Argento, Shira Goldenberg and Kate Shannon

    Citation: BMC Infectious Diseases 2019 19:212

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  16. Content type: Research article

    Repressive legal environments and widespread human rights violations act as structural impediments to efforts to engage key populations at risk of HIV infection in HIV prevention, care, and treatment efforts. ...

    Authors: Anne L. Stangl, Devaki Singh, Michael Windle, Kirsty Sievwright, Katherine Footer, Alexandrina Iovita, Stella Mukasa and Stefan Baral

    Citation: BMC Infectious Diseases 2019 19:209

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  17. Content type: Research article

    Stigma is a multifaceted concept that potentiates Human Immunodeficiency Virus and sexually transmitted infection acquisition and transmission risks among key populations, including men who have sex with men (...

    Authors: Ashley L. Grosso, Sosthenes C. Ketende, Shauna Stahlman, Odette Ky-Zerbo, Henri Gautier Ouedraogo, Seni Kouanda, Cesaire Samadoulougou, Marcel Lougue, Jules Tchalla, Simplice Anato, Sodji Dometo, Felicity D. Nadedjo, Vincent Pitche and Stefan D. Baral

    Citation: BMC Infectious Diseases 2019 19:208

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  18. Content type: Research article

    Chlamydia trachomatis infections in women continue to be a major public health concern due to their high prevalence and consequent reproductive morbidities. While antibiotics are usually efficient to clear the Ch...

    Authors: Noa Ziklo, Wilhelmina M. Huston, Kuong Taing and Peter Timms

    Citation: BMC Infectious Diseases 2019 19:218

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  19. Content type: Research article

    Human Papillomavirus (HPV) infection is estimated to be the most common sexually transmitted infection. The present systematic review summarizes data regarding the prevalence of HPV and the distribution of sub...

    Authors: Anargyros Skoulakis, Serafim Fountas, Myrto Mantzana-Peteinelli, Kleoniki Pantelidi and Efthymia Petinaki

    Citation: BMC Infectious Diseases 2019 19:192

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  20. Content type: Research article

    Antimicrobial resistance in Mycoplasma genitalium is rising globally with resultant clinical treatment failure. We investigated the prevalence of mutations in the macrolide and fluoroquinolone resistance-determin...

    Authors: Etienne E. Muller, Mahlape P. Mahlangu, David A. Lewis and Ranmini S. Kularatne

    Citation: BMC Infectious Diseases 2019 19:148

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  21. Content type: Research article

    Syphilis screening can be successfully integrated into antenatal clinics, and potentially avert significant morbidity and mortality to unborn infants. A minority of male partners report for testing and treatme...

    Authors: Edith Nakku-Joloba, Juliet Kiguli, Christine Nalwadda Kayemba, Adeline Twimukye, Joshua Kimeze Mbazira, Rosalind Parkes-Ratanshi, Monica Birungi, Joshua Kyenkya, Josaphat Byamugisha, Charlotte Gaydos and Yukari C. Manabe

    Citation: BMC Infectious Diseases 2019 19:124

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  22. Content type: Research article

    Human papillomavirus (HPV) contributes to the development of cervical and oropharyngeal tumors. The increased incidence of HPV associated oropharyngeal tumors is lately being observed also in Polish population...

    Authors: Katarzyna Kiwerska, Agata Jozefiak, Janina Markowska, Witold Kedzia, Joanna Jackowska and Malgorzata Wierzbicka

    Citation: BMC Infectious Diseases 2019 19:122

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  23. Content type: Research article

    Crowdsourcing method is an excellent tool for developing tailored interventions to improve sexual health. We evaluated the implementation of an innovation contest for sexual health promotion in China.

    Authors: Ye Zhang, Songyuan Tang, Katherine Li, Lai Sze Tso, Barry L. Bayus, David Glidden, Bin Yang, Heping Zheng, Chongyi Wei, Joseph Tucker and Weiming Tang

    Citation: BMC Infectious Diseases 2019 19:112

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  24. Content type: Research article

    To provide a scientific basis for the prevention and treatment of cervical cancer (CC), we investigated the distribution characteristics and genotypes of human papillomavirus (HPV) and the prevalence of multip...

    Authors: Xiao-wen Yuan, Yi-Jian Li, Quan Qiu, Zi-yuan Luo and Xue-feng Zhao

    Citation: BMC Infectious Diseases 2019 19:71

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  25. Content type: Research article

    Chlamydia trachomatis and Neisseria gonorrhoeae are the most common pathogens causing genital tract infections. Female commercial sex workers (FCSWs) are the key population to be affected by sexually transmitted ...

    Authors: Alelign Tadele, Siraj Hussen and Techalew Shimelis

    Citation: BMC Infectious Diseases 2019 19:61

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  26. Content type: Research article

    The incidence of Chlamydia trachomatis (Ct) urethritis has been increasing for the past 10 years. There is little data regarding the screening of Ct infection in asymptomatic men in France, despite the national r...

    Authors: Paul Rondeau, Nadia Valin, Dominique Decré, Pierre-Marie Girard, Karine Lacombe and Laure Surgers

    Citation: BMC Infectious Diseases 2019 19:31

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  27. Content type: Research article

    Genital warts are important causes of morbidity and their prevalence and incidence can be used to evaluate the impact of HPV vaccination in a population.

    Authors: Eileen O. Dareng, Sally N. Adebamowo, Ayotunde Famooto, Oluwatoyosi Olawande, Michael K. Odutola, Yinka Olaniyan, Richard A. Offiong, Paul P. Pharoah and Clement A. Adebamowo

    Citation: BMC Infectious Diseases 2019 19:27

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  28. Content type: Research article

    Extra-genital Neisseria gonorrhoeae and Chlamydia trachomatis infections are mostly asymptomatic, and important reservoir sites of infection as they often go undetected and may be more difficult to eradicate with...

    Authors: Johanna M. E. Venter, Precious M. Mahlangu, Etienne E. Müller, David A. Lewis, Kevin Rebe, Helen Struthers, James McIntyre and Ranmini S. Kularatne

    Citation: BMC Infectious Diseases 2019 19:6

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  29. Content type: Research article

    Oncogenic Human papillomavirus (HPV) infections are closely associated with anal cancer which is high among human immunodeficiency virus (HIV) infected males. There are no data regarding anal HPV infection and...

    Authors: Abhilasha Gautam, Jaya Chakravarty, Vijay Kumar Singh, Amrita Ghosh, Shashi Bhushan Chauhan, Madhukar Rai and Shyam Sundar

    Citation: BMC Infectious Diseases 2018 18:692

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  30. Content type: Research article

    The number of cases of Lymphogranuloma venereum (LGV) is increasing in Europe. The described epidemic is mostly confined to HIV positive men who have sex with men (MSM). However, dissemination of LGV from HIV ...

    Authors: Irith De Baetselier, Achilleas Tsoumanis, Ruth Verbrugge, Bénédicte De Deken, Hilde Smet, Saïd Abdellati, Vicky Cuylaerts, Ludwig Apers and Tania Crucitti

    Citation: BMC Infectious Diseases 2018 18:689

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  31. Content type: Research article

    A high rectal and oropharyngeal sexually transmitted infection (STI) burden has been reported among men who have sex with men (MSM) in many regions, but little data exists on rectal and oropharyngeal STIs amon...

    Authors: Li-Gang Yang, Xiao-Hui Zhang, Pei-Zhen Zhao, Zheng-Yu Chen, Wu-Jian Ke, Xu-Qi Ren, Liu-Yuan Wang, Wei-Ying Chen and Joseph D. Tucker

    Citation: BMC Infectious Diseases 2018 18:675

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  32. Content type: Research article

    Nucleic acid amplification tests (NAAT) are well-accepted in diagnosis and surveillance of sexually infectious pathogens worldwide. However, performance differences between a RNA-based NAAT and DNA-based NAAT ...

    Authors: Yuying Liang, Xin Jin, Fang Yuan, Zhanjia Li and Shuiping Chen

    Citation: BMC Infectious Diseases 2018 18:651

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  33. Content type: Research article

    In the Netherlands, there are strong disparities in Chlamydia trachomatis (CT) prevalence between ethnic groups. The current study aims to identify whether socioeconomic status, sexual risk behavior and sexual he...

    Authors: Sebastiaan H. Hulstein, Amy Matser, Catharina J. Alberts, Marieke B. Snijder, Martina Willhauck-Fleckenstein, Katrin Hufnagel, Maria Prins, Henry J. C. de Vries, Maarten F. Schim van der Loeff and Tim Waterboer

    Citation: BMC Infectious Diseases 2018 18:612

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  34. Content type: Research article

    The European Gonococcal Antimicrobial Surveillance Programme (Euro-GASP) performs annual sentinel surveillance of Neisseria gonorrhoeae susceptibility to therapeutically relevant antimicrobials across the Europea...

    Authors: Michaela J. Day, Gianfranco Spiteri, Susanne Jacobsson, Neil Woodford, Andrew J. Amato-Gauci, Michelle J. Cole and Magnus Unemo

    Citation: BMC Infectious Diseases 2018 18:609

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  35. Content type: Research article

    The increasing prevalence of macrolide resistant Mycoplasma genitalium is a major concern worldwide. In Cuba, several cases of clinical treatment failure with 1 g single dose and extended azithromycin regimen hav...

    Authors: Brian Arturo Mondeja, Javier Couri, Nadia Maria Rodríguez, Orestes Blanco, Carmen Fernández and Jørgen Skov Jensen

    Citation: BMC Infectious Diseases 2018 18:601

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  36. Content type: Research article

    Chlamydia trachomatis is the most common curable sexual transmitted bacterial infection in the world, including Sub-Saharan Africa. There is nil systematic review and meta-analysis on Chlamydia trachomatis infect...

    Authors: Siraj Hussen, Demelash Wachamo, Zemenu Yohannes and Endale Tadesse

    Citation: BMC Infectious Diseases 2018 18:596

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  37. Content type: Research article

    HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a progressive neurological and inflammatory disease, associated with HTLV-1 infection. HAM/TSP neurological disease is a consequence of an...

    Authors: Doris Schor, Luís Cristóvão Porto, Eric Henrique Roma, Marcel de Souza Borges Quintana, Gustavo Milson Fabricio-Silva, Maria Gloria Bonecini-Almeida, Abelardo Queiroz-Campos Araújo and Maria Jose Andrada-Serpa

    Citation: BMC Infectious Diseases 2018 18:593

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  38. Content type: Study protocol

    Cervical cancer (CC) is caused by a persistent infection of high-risk human papillomavirus (HR-HPV). While most HPV infections are transient, persistent HPV infections are a significant health problem in Mexic...

    Authors: K. Torres-Poveda, M. Bahena-Román, K. Delgado-Romero and V. Madrid-Marina

    Citation: BMC Infectious Diseases 2018 18:582

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  39. Content type: Study protocol

    Chlamydia trachomatis (chlamydia), the most commonly reported sexually transmitted infection (STI) in the Netherlands, can lead to severe reproductive complications. Reasons for the sustained chlamydia prevalence...

    Authors: Daphne A. van Wees, Janneke C. M. Heijne, Titia Heijman, Karlijn C. J. G. Kampman, Karin Westra, Anne de Vries, Mirjam E. E. Kretzschmar and Chantal den Daas

    Citation: BMC Infectious Diseases 2018 18:559

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  40. Content type: Research article

    Screening of curable sexually transmitted infections is frequently oriented towards the diagnosis of chlamydia, gonorrhea, syphilis and trichomoniasis, whereas other pathogens, sometimes associated with simila...

    Authors: Simon C. Masha, Piet Cools, Patrick Descheemaeker, Marijke Reynders, Eduard J. Sanders and Mario Vaneechoutte

    Citation: BMC Infectious Diseases 2018 18:549

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  41. Content type: Research article

    In recent decades the epidemic of asymptomatic sexually transmitted infections has extended deep into Brazil, including small towns and rural areas. The purpose of this study was to investigate the epidemiolog...

    Authors: Déborah Ferreira Noronha de Castro Rocha, Luana Rocha da Cunha Rosa, Carla de Almeida Silva, Brunna Rodrigues de Oliveira, Thaynara Lorrane Silva Martins, Regina Maria Bringel Martins, Marcos André de Matos, Megmar Aparecida dos Santos Carneiro, Juliana Pontes Soares, Ana Cristina de Oliveira e Silva, Márcia Maria de Souza, Robert L. Cook, Karlla Antonieta Amorim Caetano and Sheila Araujo Teles

    Citation: BMC Infectious Diseases 2018 18:546

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  42. Content type: Research article

    Incarcerated people carry a high burden of infection, including blood-borne diseases (BBDs). It is also known that one million people contract a sexually transmitted infection (STI) every day worldwide, which ...

    Authors: Komal Chacowry Pala, Stéphanie Baggio, Nguyen Toan Tran, François Girardin, Hans Wolff and Laurent Gétaz

    Citation: BMC Infectious Diseases 2018 18:539

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  43. Content type: Research article

    A population-based study of Chlamydia trachomatis (CT) infections is essential in designing a specific control program; however, no large investigation of CT infections among the general population in mainland Ch...

    Authors: Pengcheng Huai, Furong Li, Zhen Li, Lele Sun, Xi’an Fu, Qing Pan, Gongqi Yu, Zemin Chai, Tongsheng Chu, Zihao Mi, Fangfang Bao, Honglei Wang, Bingni Zhou, Chuan Wang, Yonghu Sun, Guiye Niu…

    Citation: BMC Infectious Diseases 2018 18:534

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  44. Content type: Research article

    Human papillomavirus (HPV), Epstein-Barr virus (EBV) and herpes simplex virus (HSV) cause sexually transmitted diseases (STDs) that are frequently found in men who have sex with men (MSM) with human immunodeficie...

    Authors: Jureeporn Chuerduangphui, Kanisara Proyrungroj, Chamsai Pientong, Saowarop Hinkan, Jiratha Budkaew, Charinya Pimson, Bandit Chumworathayi, Ploenpit Hanond and Tipaya Ekalaksananan

    Citation: BMC Infectious Diseases 2018 18:509

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  45. Content type: Research article

    Ascertaining if the clinical and immunological response to repeat syphilis differs from that in initial syphilis may assist in designing optimal syphilis screening strategies and vaccine design.

    Authors: Chris Kenyon, Kara Krista Osbak, Tania Crucitti and Luc Kestens

    Citation: BMC Infectious Diseases 2018 18:479

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  46. Content type: Research article

    Chlamydia trachomatis and Neisseria gonorrhoeae are the two common transmissible pathogens from pregnant women to their neonates. Given the lack of routine screening and treatment of pregnant women in some areas,...

    Authors: Bahman Pourabbas, Zahra Rezaei, Jalal Mardaneh, Mozhgan Shahian and Abdolvahab Alborzi

    Citation: BMC Infectious Diseases 2018 18:477

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  47. Content type: Research article

    Infection with Chlamydia trachomatis (Ct) is the most commonly reported sexually transmitted infection in Europe. In Germany, Ct screening is offered free of charge to pregnant women since 1995 and to women < 25 ...

    Authors: Alexandra Sarah Lang, Matthias an der Heiden, Klaus Jansen, Andrea Sailer, Viviane Bremer and Sandra Dudareva

    Citation: BMC Infectious Diseases 2018 18:424

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  48. Content type: Research article

    Herpes simplex virus infection is a global health concern with disproportionately high burden in low and middle-income countries. There is a paucity of data on the prevalence of HSV infection in Ghana, which n...

    Authors: Oksana Debrah, Francis Agyemang-Yeboah, Richard Harry Asmah, Emmanuel Timmy-Donkoh, Mohammed Mustapha Seini, Linda Ahenkorah Fondjo, Nilok Sight and Ellis Owusu-Dabo

    Citation: BMC Infectious Diseases 2018 18:378

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