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Parasitological diseases

Section edited by Honorine Ward & Laith Yakob 

This section aims to publish studies looking at all aspects of the prevention, diagnosis and management of parasitological diseases in humans, as well as related studies on molecular and cellular biology, pathophysiology, and epidemiology.

Page 1 of 8

  1. Content type: Research article

    Human leishmaniasis is one of the major parasitic diseases with worldwide distribution. Sri Lanka is a recently established focus of leishmaniasis caused by a variant Leishmania donovani. Early case detection and...

    Authors: Bhagya Deepachandi, Sudath Weerasinghe, Preethi Soysa, Nadira Karunaweera and Yamuna Siriwardana

    Citation: BMC Infectious Diseases 2019 19:623

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  2. Content type: Research article

    Intestinal helminth infections are a serious public health problem in developing countries. Jiangsu, an eastern coastal province of China, has an environment conducive to the transmission of intestinal parasit...

    Authors: Yang Dai, Xiangzhen Xu, Jianfeng Liu, Xiaolin Jin, Mingxue Shen, Xiaoting Wang, Jun Cao and Haitao Yang

    Citation: BMC Infectious Diseases 2019 19:604

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  3. Content type: Research article

    Oxidative stress plays a vital role in the pathogenesis of both Sickle Cell Disease (SCD) and Plasmodium falciparum malaria. However, there are limited studies on the effect of P. falciparum malaria infection on ...

    Authors: Saad Mahjub Atiku, Nabukeera Louise and Dennis M. Kasozi

    Citation: BMC Infectious Diseases 2019 19:600

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  4. Content type: Technical advance

    Current drug regimens for cutaneous leishmaniasis (CL) include toxic systemic therapies such as amphotericin B (AB) and pentavalent antimonials. Fluconazole (FZ) is a well-tolerated potential oral alternative ...

    Authors: Ruwandi Kariyawasam, Priyanka Challa, Rachel Lau and Andrea K. Boggild

    Citation: BMC Infectious Diseases 2019 19:593

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  5. Content type: Research article

    Toxoplasmosis is caused by an obligatory intracellular coccidian protozoan organism, Toxoplasma gondii. It has a worldwide distribution, affecting one-third of the world population. Psychiatric patients have a hi...

    Authors: Barnabas Achaw, Habtie Tesfa, Ayalew Jejaw Zeleke, Ligabaw Worku, Ayenew Addisu, Niguse Yigzaw and Yalewayker Tegegne

    Citation: BMC Infectious Diseases 2019 19:581

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  6. Content type: Research article

    Pleural parasitic infestation (PPI) is a disease prevalent in certain parts of the world. It is frequently misdiagnosed due to its lack of standardized diagnostic criteria. The purpose of this study was to eva...

    Authors: Jinlin Wang, Weizhan Luo, Panxiao Shen, Jianxing He and Yunxiang Zeng

    Citation: BMC Infectious Diseases 2019 19:576

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  7. Content type: Research article

    Blood smear microscopy remains the gold-standard method to diagnose and quantify malaria parasite density. In addition, parasite genotyping of select loci is the most utilized method for distinguishing recrude...

    Authors: Aine Lehane, Moses Were, Martina Wade, Musleehat Hamadu, Megan Cahill, Sylvia Kiconco, Richard Kajubi, Francesca Aweeka, Norah Mwebaza, Fangyong Li and Sunil Parikh

    Citation: BMC Infectious Diseases 2019 19:559

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  8. Content type: Research article

    Intestinal parasitic infections are still common in low-income countries including Ethiopia, particularly in children due to low-quality drinking water, poor personal and environmental sanitation. Disabled ind...

    Authors: Agumas Ayalew Fentahun, Anemaw Asrat, Abebayehu Bitew and Selamawit Mulat

    Citation: BMC Infectious Diseases 2019 19:549

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  9. Content type: Case report

    Cysticercosis is an emerging and neglected tropical disease (NTD) that poses a serious public health concern worldwide. Disseminated cysticercosis (DCC) is an uncommon manifestation of cysticercosis, also foun...

    Authors: Yang Zou, Fei Wang, Hong-Bin Wang, Wayne W. Wu, Chia-Kwung Fan, Han-Yu Zhang, Lei Wang, Xiao-Jun Tian, Wei Li and Min-Jun Huang

    Citation: BMC Infectious Diseases 2019 19:543

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  10. Content type: Research article

    Enterobius vermicularis (pinworm) is one of the most common human parasitic helminths, and children are the most susceptible group. Some behavioral and environmental factors may facilitate pinworm infection. In t...

    Authors: Chia-Kwung Fan, Ting-Wu Chuang, Ying-Chieh Huang, Ai-Wen Yin, Chia-Mei Chou, Yu-Ting Hsu, Ramson Kios, Shao-Lun Hsu, Ying-Ting Wang, Mai-Szu Wu, Jia-Wei Lin, Kennar Briand and Chia-Ying Tu

    Citation: BMC Infectious Diseases 2019 19:536

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  11. Content type: Case report

    Cysticercosis is spreading all over the world and it is a major health problem in most countries of Latin America, Africa, and Asia. Extensive disseminated cysticercosis is relatively rare and fewer than 120 c...

    Authors: Xin-Zhong Zang, Huan-Zhang Li, Men-Bao Qian, Ying-Dan Chen, Chang-Hai Zhou, Hong-Kun Liu, Yu-Hua Liu and Shi-Zhu Li

    Citation: BMC Infectious Diseases 2019 19:535

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  12. Content type: Case report

    Food-borne trematodiases are an important group of neglected global diseases. Affected patients in regions with low prevalence usually experience delayed diagnosis, especially when presenting with atypical cli...

    Authors: Lun Li, Xinchao Liu, Baotong Zhou, Shimin Zhang, Geng Wang, Guotao Ma, Ruxuan Chen, Yang Zou, Wei Cao and Taisheng Li

    Citation: BMC Infectious Diseases 2019 19:526

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  13. Content type: Research article

    Schistosomiasis remains a public health problem in Central Kenya despite concerted control efforts. Access to improved water and sanitation has been emphasized as important control measures. Few studies have a...

    Authors: Paul M. Gichuki, Stella Kepha, Damaris Mulewa, Janet Masaku, Celestine Kwoba, Gabriel Mbugua, Humphrey D. Mazigo and Charles Mwandawiro

    Citation: BMC Infectious Diseases 2019 19:503

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  14. Content type: Research article

    An estimated 60% of the world’s population is infected with one form of intestinal parasites. Amoebiasis and giardiasis are among the leading intestinal protozoan infections that affected mankind. However, lit...

    Authors: Behailu Hawulte Ayele, Ayele Geleto, Desalegn Admassu Ayana and Muhedin Redi

    Citation: BMC Infectious Diseases 2019 19:499

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  15. Content type: Research article

    Previous studies reported contradicting findings about the association between intestinal parasitosis and maternal anemia. In this study we aimed to determine the prevalence of intestinal parasitic infection a...

    Authors: Amelo Bolka and Samson Gebremedhin

    Citation: BMC Infectious Diseases 2019 19:483

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  16. Content type: Research article

    Some reports are available on the prevalence of opportunistic parasitoses among hemodialysis (HD) patients, yet there is a paucity of data on the association of CD4+ T-cell counts with such infections. Therefo...

    Authors: Amany I. Shehata, Faika Hassanein and Rashad Abdul-Ghani

    Citation: BMC Infectious Diseases 2019 19:480

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  17. Content type: Research article

    Onchocerciasis is caused by a nematode worm Onchocerca volvulus, which is transmitted in Sudan by black fly vectors of the Simulium damnosum sensu lato species complex. In Sudan, the disease is found in four foci...

    Authors: Isam M. A. Zarroug, Arwa Elaagip, Suhaib G. Gumaa, Altayeb K. Ali, Ayman Ahmed, Hanaa A. M. Siam, Deena M. Abdelgadir, Olabanji A. Surakat, Olatunwa J. Olamiju, Daniel A. Boakye, Nabil Aziz and Kamal Hashim

    Citation: BMC Infectious Diseases 2019 19:477

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  18. Content type: Research article

    Visceral Leishmaniasis (VL) is caused by a protozoan parasite Leishmania donovani that is transmitted to humans by an infected female sandfly, Phlebotomus argentipes. VL is common in the Indian sub-continent incl...

    Authors: Mitesh Shrestha, Medha Khatri-Chhetri, Ram Chandra Poudel, Jyoti Maharjan, Shyam Prakash Dumre, Krishna Das Manandhar, Basu Dev Pandey, Sher Bahadur Pun and Kishor Pandey

    Citation: BMC Infectious Diseases 2019 19:444

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  19. Content type: Research article

    Lymphatic Filariasis (LF) is a vector-borne neglected tropical disease caused by the filarial nematode parasites that can lead to the disfiguring swelling of the limbs (lymphedema or elephantiasis for late sta...

    Authors: Alexander Kwarteng, Yarhands Dissou Arthur, John Kanyiri Yamba, Augustina A. Sylverken, Priscilla Kini, Samuel Terkper Ahuno and Ellis Owusu-Dabo

    Citation: BMC Infectious Diseases 2019 19:442

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  20. Content type: Research article

    Onchocerciasis is a neglected tropical disease which is still of immense major public health concern in several areas of Africa and the Americas. The disease manifests either as ocular or as dermal onchocercia...

    Authors: Kenneth Bentum Otabil, Samuel Fosu Gyasi, Esi Awuah, Daniels Obeng-Ofori, Robert Junior Atta-Nyarko, Dominic Andoh, Beatrice Conduah, Lawrence Agbenyikey, Philip Aseidu, Comfort Blessing Ankrah, Abdul Razak Nuhu and H. D. F. H. Schallig

    Citation: BMC Infectious Diseases 2019 19:431

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  21. Content type: Research article

    Malaria continues to be a public health problem and important cause of morbidity and mortality in Ethiopia. Due to continuous interventions to combat malaria in endemic regions, a decline in malaria related de...

    Authors: Teha Shumbej, Abdulewhab Jemal, Abdulsemed Worku, Fitsum Bekele and Habtamu Weldesenbet

    Citation: BMC Infectious Diseases 2019 19:413

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  22. Content type: Research article

    Consumption of unwashed, raw or unhygienically prepared fruits and vegetables act as potential source for the spread of various parasitic diseases. Moreover, the level of contamination and species of contamina...

    Authors: Getaneh Alemu, Mohammedaman Mama, Direslgne Misker and Desta Haftu

    Citation: BMC Infectious Diseases 2019 19:410

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  23. Content type: Research article

    In co-endemic areas, rate of intestinal parasites and tuberculosis (TB) co-infection thought to be high. However, there are limited studies on the epidemiology of this co-infection in Ethiopia. Therefore, the ...

    Authors: Ayinalem Alemu, Abebaw Kebede, Biniyam Dagne, Misikir Amare, Getu Diriba, Bazezew Yenew, Ephrem Tesfaye, Mengistu Tadesse, Waganeh Sinshaw, Dawit Challa and Kassu Desta

    Citation: BMC Infectious Diseases 2019 19:407

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  24. Content type: Research article

    In Ethiopia, like other developing countries, intestinal parasitic infections are the major public health problems affecting millions annually. Overcrowding and poor living conditions are the major risk factor...

    Authors: Fitsum Mardu, Mekonnen Yohannes and Desalegn Tadesse

    Citation: BMC Infectious Diseases 2019 19:406

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  25. Content type: Research article

    Quinine (QN) remains an effective drug for malaria treatment. However, quinine resistance (QNR) in Plasmodium falciparum has been reported in many malaria-endemic regions particularly in African countries. Geneti...

    Authors: Kai Wu, Yi Yao, Fang Chen, Mingxing Xu, Guangquan Lu, Tingting Jiang, Ziyu Liu, Weixing Du, Fang Li, Rugui Li, Huabing Tan and Jian Li

    Citation: BMC Infectious Diseases 2019 19:354

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  26. Content type: Research article

    Intestinal parasitic infections (IPIs) have been major public health problems in low income countries primarily affecting school children. Previous studies in Ethiopia have shown high burden of intestinal para...

    Authors: Baye Sitotaw, Haileyesus Mekuriaw and Destaw Damtie

    Citation: BMC Infectious Diseases 2019 19:341

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  27. Content type: Research article

    Lymphatic filariasis (LF) is a mosquito-borne parasitic disease and a major cause of disability worldwide. To effectively plan morbidity management programmes, it is important to estimate disease burden and ev...

    Authors: Obiora A. Eneanya, Tini Garske and Christl A. Donnelly

    Citation: BMC Infectious Diseases 2019 19:332

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  28. Content type: Research article

    In Vietnam, few studies have determined the epidemiological status of toxoplasmosis in pregnant women and no routine prenatal screening is in place. This study was conducted to evaluate the seroprevalence of t...

    Authors: G. Suzanne A. Smit, Binh Thi Lam Vu, Dung Trung Do, Quan Ha Do, Huy Quang Pham, Niko Speybroeck, Brecht Devleesschauwer, Elizaveta Padalko, Ellen Roets and Pierre Dorny

    Citation: BMC Infectious Diseases 2019 19:329

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  29. Content type: Case report

    Visceral leishmaniasis is a vector-borne parasitic disease caused by protozoa belonging to the genus Leishmania. The clinical presentation of visceral leishmaniasis strictly depends on the host immunocompetency, ...

    Authors: Claudia Colomba, Laura Saporito, Paola Di Carlo, Manlio Tolomeo, Adriana Cervo, Alberto Firenze, Marcello Trizzino and Antonio Cascio

    Citation: BMC Infectious Diseases 2019 19:328

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  30. Content type: Research article

    Toxoplasma gondii infection is a great health concern to pregnant women and the developing fetus. The aim of this study was to determine the seroprevalence of T. gondii and its associated factors in Adwa district...

    Authors: Mebrahtu Teweldemedhin, Amaha Gebremichael, Gebretsadkan Geberkirstos, Haftom Hadush, Tuam Gebrewahid, Solomon Weldegebreal Asgedom, Berihu Gidey, Negasi Asres and Hailay Gebreyesus

    Citation: BMC Infectious Diseases 2019 19:327

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  31. Content type: Research article

    Cutaneous leishmaniasis (CL) is an important public health problem in Brazil and in several tropical regions of the world. In the Americas, Brazil is the country with the highest number of registered cases. In...

    Authors: Diogo Tavares Cardoso, Dayane Costa de Souza, Vanessa Normandio de Castro, Stefan Michael Geiger and David Soeiro Barbosa

    Citation: BMC Infectious Diseases 2019 19:318

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  32. Content type: Research article

    The prevalence of Plasmodium falciparum and Intestinal Parasitic Infections (IPIs) - with the corresponding pathogenesis among children remain uncertain. This study aimed at determining the prevalence and the out...

    Authors: Paul Oboth, Yahaya Gavamukulya and Banson John Barugahare

    Citation: BMC Infectious Diseases 2019 19:295

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  33. Content type: Research article

    Intestinal parasites still pose major public health problems in developing countries like Ethiopia. Local epidemiological data is indispensable in order to design and monitor prevention and control strategies....

    Authors: Getaneh Alemu, Ashenafi Abossie and Zerihun Yohannes

    Citation: BMC Infectious Diseases 2019 19:270

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  34. Content type: Study protocol

    Soil-transmitted helminthiasis affects almost 2 billion people worldwide in tropical climates. Preventive chemotherapy, using the benzimidazoles (albendazole and mebendazole) is the current main recommended co...

    Authors: Chandni Patel, Eveline Hürlimann, Ladina Keller, Jan Hattendorf, Somphou Sayasone, Said M Ali, Shaali M Ame, Jean T Coulibaly and Jennifer Keiser

    Citation: BMC Infectious Diseases 2019 19:262

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  35. Content type: Research article

    Environmental, social, geographical, and other factors could affect the distribution of intestinal parasites. Parasitic infections would impose on health and social problems like mal-absorption, diarrhea, impa...

    Authors: Habtamu Sewunet Mekonnen and Daniale Tekelia Ekubagewargies

    Citation: BMC Infectious Diseases 2019 19:256

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  36. Content type: Research article

    Chronic Chagas Disease (CD) diagnosis is based on serological methods employing crude, semipurified or recombinant antigens, which may result in low sensitivity or cross-reactivity. To reduce these restriction...

    Authors: Eva Dopico, Rodrigo Pimenta Del-Rei, Bertha Espinoza, Itziar Ubillos, Nilson Ivo Tonin Zanchin, Elena Sulleiro, Zaira Moure, Paola Alejandra Fiorani Celedon, Wayner Vieira Souza, Edimilson Domingos da Silva, Yara Miranda Gomes and Fred Luciano Neves Santos

    Citation: BMC Infectious Diseases 2019 19:251

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  37. Content type: Research article

    The WHO recommends single low-dose primaquine (SLDPQ, 0.25 mg/kg body weight) in falciparum-infected patients to block malaria transmission and contribute to eliminating multidrug resistant Plasmodium falciparum ...

    Authors: Lek Dysoley, Saorin Kim, Sergio Lopes, Nimol Khim, Steven Bjorges, Samphornarann Top, Chea Huch, Huy Rekol, Nelli Westercamp, Mark M. Fukuda, Jimee Hwang, Arantxa Roca-Feltrer, Mavuto Mukaka, Didier Menard and Walter R. Taylor

    Citation: BMC Infectious Diseases 2019 19:250

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  38. Content type: Research article

    Malaria and leishmaniasis are the two largest parasitic killers in the world. Due togeographical overlap of these diseases, malaria-visceral leishmaniasis co-infections occur in large populations and exist in ...

    Authors: Yibeltal Aschale, Animen Ayehu, Ligabaw Worku, Habtie Tesfa, Meseret Birhanie and Wossenseged Lemma

    Citation: BMC Infectious Diseases 2019 19:239

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  39. Content type: Research article

    Schistosomiasis is a devastating parasitic disease. The mainstay of schistosomiasis control is by praziquantel treatment. The study aimed to determine benefits of annual chemotherapy of schistosomiasis on deve...

    Authors: Tawanda J. Chisango, Bongiwe Ndlovu, Arthur Vengesai, Agness Farai Nhidza, Edson P. Sibanda, Danai Zhou, Francisca Mutapi and Takafira Mduluza

    Citation: BMC Infectious Diseases 2019 19:219

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  40. Content type: Research article

    Accurate diagnosis of Toxoplasma gondii (T. gondii) infection remains elusive and requires a comprehensive assessment through laboratory and clinical investigation. In this study, a diagnostic algorithm based on ...

    Authors: Padmaloseni Thangarajah, Khalid Hajissa, Weng Kin Wong, Muhammad Amiruddin Abdullah, Nabilah Ismail and Zeehaida Mohamed

    Citation: BMC Infectious Diseases 2019 19:202

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  41. Content type: Research article

    Infestations with scabies mites are a global burden affecting individuals of all ages, classes and ethnicities. As poor sanitation and overcrowding favor the transmission of this highly contagious disease, epi...

    Authors: Simon M. Mueller, Stefan Gysin, Michael Schweitzer, Simon Schwegler, Peter Haeusermann, Peter Itin, Thomas Bart, Ruth Spieler Denz, Thomas Steffen, Richard Kuehl, Andreas F. Widmer and Oliver Brandt

    Citation: BMC Infectious Diseases 2019 19:200

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  42. Content type: Research article

    Parasitic infections, particularly those caused by protozoa, represent a considerable public health problem in developing countries. Blastocystis, Giardia duodenalis, Cryptosporidium spp. and the Entamoeba comple...

    Authors: Ximena Villamizar, Adriana Higuera, Giovanny Herrera, Luis Reinel Vasquez-A, Lorena Buitron, Lina Maria Muñoz, Fabiola E. Gonzalez-C, Myriam Consuelo Lopez, Julio Cesar Giraldo and Juan David Ramírez

    Citation: BMC Infectious Diseases 2019 19:190

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  43. Content type: Debate

    Taenia solium taeniosis/cysticercosis is a public health and agricultural problem, especially in low-income countries, and has been ranked the top foodborne parasitic hazard globally. In 2012, the World Health Or...

    Authors: Uffe Christian Braae, Sarah Gabriël, Chiara Trevisan, Lian F. Thomas, Pascal Magnussen, Bernadette Abela-Ridder, Helena Ngowi and Maria Vang Johansen

    Citation: BMC Infectious Diseases 2019 19:182

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  44. Content type: Research article

    Prevalence of schistosomiasis is high among children under five years in Uganda. Schistosomiasis control efforts over time have included periodic mass treatments in endemic areas for adults and school going ch...

    Authors: Simon Peter Sebina Kibira, John C. Ssempebwa, Ronald Ssenyonga, Scott Radloff and Fredrick Edward Makumbi

    Citation: BMC Infectious Diseases 2019 19:165

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  45. Content type: Research article

    Loiasis is a vector-borne parasitic disease due to Loa loa and transmitted to humans by tabanids of the genus Chrysops. Loiasis has been historically considered as the second or third most common reason for medic...

    Authors: Aude E. Mogoung-Wafo, Hugues C. Nana-Djeunga, André Domche, Floribert Fossuo-Thotchum, Jean Bopda, Steve Mbickmen-Tchana, Honoré Djomo-Kamga and Joseph Kamgno

    Citation: BMC Infectious Diseases 2019 19:146

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  46. Content type: Research article

    Soil-transmitted helminthic (STH) infections are common in Sub-Saharan Africa. One method used for control of these helminths is mass anti-helminthic administration in populations at risk of STH infections. In...

    Authors: Abdulazeez Imam, Zubaida L. Farouk, Fatimah Hassan-Hanga and Uchechukwu G. Ihesiulor

    Citation: BMC Infectious Diseases 2019 19:121

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  47. Content type: Case report

    Clonorchiasis is the common parasitic infection in the general population of the Republic of Korea, however, taeniasis is scarcely reported recently. Here, we describe a case of co-infection with the cestode T. s...

    Authors: Ju Hyeon Shin, Eun Jeong Won, Jee Seung Jung, Kyung-Hwa Park, Kwang Il Nam, Soo Hyun Kim and Jong Hee Shin

    Citation: BMC Infectious Diseases 2019 19:115

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  48. Content type: Research article

    Cutaneous leishmaniasis (CL) caused by Leishmania species, is a geographically extensive disease that infects humans and animals. CL is endemic in half of the 31 provinces of Iran, with 29,201 incidence cases rep...

    Authors: Iraj Mohammadpour, Gholam Reza Hatam, Farhad Handjani, Farzaneh Bozorg-Ghalati, Daniel PourKamal and Mohammad Hossein Motazedian

    Citation: BMC Infectious Diseases 2019 19:98

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  49. Content type: Research article

    Making a definite diagnosis of infectious uveitis is a challenging task because many other infectious, and non-infectious uveitis, may have similar non-specific symptoms and overlapping clinical appearances. C...

    Authors: Alejandra de-la-Torre, Juanita Valdés-Camacho, Clara López de Mesa, Andrés Uauy-Nazal, Juan David Zuluaga, Lina María Ramírez-Páez, Felipe Durán, Elizabeth Torres-Morales, Jessica Triviño, Mateo Murillo, Alba Cristina Peñaranda, Juan Carlos Sepúlveda-Arias and Jorge Enrique Gómez-Marín

    Citation: BMC Infectious Diseases 2019 19:91

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