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Bacterial and fungal diseases

Section edited by Ivan FN Hung, Jorge Garbino and Kelvin To

This section aims to publish studies looking at all aspects of the prevention, diagnosis and management of bacterial and fungal diseases in humans, as well as related molecular genetics, pathophysiology, and epidemiology. This section includes studies relating to antibiotic resistance and healthcare-associated infections.

Page 1 of 31

  1. Content type: Research article

    Globally, diarrhea is the leading cause of morbidity and mortality among less than 5 years old children and it contributes to the deaths of approximately one million children every year. In Ethiopia, diarrhea ...

    Authors: Getachew Yismaw Workie, Temesgen Yihunie Akalu and Adhanom Gebreegziabher Baraki

    Citation: BMC Infectious Diseases 2019 19:804

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  2. Content type: Research article

    In Nepal, cases of Cholera occur annually either as sporadic or as outbreaks claiming the lives of many in rural areas. The present study is a laboratory based surveillance which aims to analyze the changing e...

    Authors: Nisha Rijal, Jyoti Acharya, Shailaja Adhikari, Bishnu Psd Upadhaya, Geeta Shakya, Palpasa Kansakar and Piyush Rajbhandari

    Citation: BMC Infectious Diseases 2019 19:801

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  3. Content type: Case report

    The number of new rickettsial species are rapidly increasing, and increasing numbers of Rickettsia raoultii (R. raoultii) infection cases have been detected in humans. However, neurological abnormalities caused b...

    Authors: Zhihui Dong, Yicheng Yang, Qian Wang, Songsong Xie, Shanshan Zhao, Wenbo Tan, Wumei Yuan and Yuanzhi Wang

    Citation: BMC Infectious Diseases 2019 19:796

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  4. Content type: Research article

    Bacteria of the Achromobacter genus, more particularly xylosoxidans species, are responsible for various healthcare associated infections (HAI) which are increasingly described since the last decade. Cystic fibro...

    Authors: Karine Marion-Sanchez, Karine Pailla, Claude Olive, Xavier Le Coutour and Christian Derancourt

    Citation: BMC Infectious Diseases 2019 19:795

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  5. Content type: Research article

    Infections by Streptococcus gallolyticus subsp. pasteurianus (SGSP) is often underestimated. Herein, the epidemiological features and resistant characteristics of SGSP in mainland China are characterized to enabl...

    Authors: Yi Li, Xingchun Chen, Zhijun Zhang, Lijun Wang, Junrui Wang, Ji Zeng, Junwen Yang and Binghuai Lu

    Citation: BMC Infectious Diseases 2019 19:791

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  6. Content type: Research article

    Genetic variant is one of the causes of sepsis patients’ mortality. Now, many studies have identified several SNPs related to sepsis. However, none of these studies were identified in a genome-wide way. We aim...

    Authors: Huijuan Wang, Zhaohui Tong, Jia Li, Kun Xiao, Feifei Ren and Lixin Xie

    Citation: BMC Infectious Diseases 2019 19:781

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  7. Content type: Study protocol

    Sepsis is still a common critical disease with high morbidity and mortality in intensive care unit. Despite published guidelines for sepsis, development of antibiotic therapy and advanced organ support technol...

    Authors: Zhigang Zhou, Tienan Feng, Yun Xie, Peijie Huang, Hui Xie, Rui Tian, Biyun Qian and Ruilan Wang

    Citation: BMC Infectious Diseases 2019 19:780

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  8. Content type: Case report

    Splenic abscess usually arises from hematogenous spread. Causative pathogens are various and anaerobic pathogens are rarely reported.

    Authors: Jeremy Meyer, Arnaud Dupuis, Benedikt D. Huttner, Matthieu Tihy and Léo Bühler

    Citation: BMC Infectious Diseases 2019 19:777

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  9. Content type: Research article

    Carbapenem-resistant Enterobacteriaceae (CRE) represent an important global threat. The aim of this study is to describe the clinical course and outcomes of patients with CRE infections treated with ceftazidime-a...

    Authors: Basem M. Alraddadi, Mohammed Saeedi, Mohammed Qutub, Abeer Alshukairi, Ashraf Hassanien and Ghassan Wali

    Citation: BMC Infectious Diseases 2019 19:772

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  10. Content type: Research article

    Health-workers in developing countries rely on clinical algorithms, such as the Integrated Management of Childhood Illnesses (IMCI), for the management of patients, including diagnosis of serious bacterial inf...

    Authors: Kristina Keitel, Mary Kilowoko, Esther Kyungu, Blaise Genton and Valérie D’Acremont

    Citation: BMC Infectious Diseases 2019 19:769

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  11. Content type: Research article

    Bacterial ophthalmic infections are common. Empirical treatment with topical broad-spectrum antibiotics is recommended for severe cases. Antimicrobial resistance (AMR) to agents used for bacterial ophthalmic i...

    Authors: Alice E. Lee, Kanchana Niruttan, Timothy M. Rawson and Luke S. P. Moore

    Citation: BMC Infectious Diseases 2019 19:768

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  12. Content type: Case report

    Actinomycetes can rarely cause intracranial infection and may cause a variety of complications. We describe a fatal case of intracranial and intra-orbital actinomycosis of odontogenic origin with a unique present...

    Authors: G. J. Hötte, M. J. Koudstaal, R. M. Verdijk, M. J. Titulaer, J. F. H. M. Claes, E. M. Strabbing, A. van der Lugt and D. Paridaens

    Citation: BMC Infectious Diseases 2019 19:763

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  13. Content type: Research article

    Aspiration pneumonia is a serious problem among elderly patients; it is caused by many risk factors including dysphagia, poor oral hygiene, malnutrition, and sedative medications. The aim of this study was to ...

    Authors: Tomotaka Nishizawa, Yuichi Niikura, Keiichi Akasaka, Masato Watanabe, Daisuke Kurai, Masako Amano, Haruyuki Ishii, Hidekazu Matsushima, Naomi Yamashita and Hajime Takizawa

    Citation: BMC Infectious Diseases 2019 19:761

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  14. Content type: Research article

    Early diagnosis of sepsis in pediatric patients is vital but remains a major challenge. Previous studies showed that presepsin is potentially a reliable diagnostic biomarker for sepsis in adult and neonates. H...

    Authors: Seo Hee Yoon, Eun Hwa Kim, Ha Yan Kim and Jong Gyun Ahn

    Citation: BMC Infectious Diseases 2019 19:760

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  15. Content type: Research article

    Surveillance of current changes in the epidemiology of Invasive Fungal Diseases (IFDs) as an important component of the antifungal stewardship programs (ASP), requires careful regular monitoring, especially in hi...

    Authors: Seyedeh Sedigheh Hamzavi, Ali Amanati, Parisa Badiee, Mohammad Rahim Kadivar, Hadis Jafarian, Fatemeh Ghasemi, Sezaneh Haghpanah, Mansooreh Dehghani and Abbas Norouzian Baghani

    Citation: BMC Infectious Diseases 2019 19:759

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  16. Content type: Research article

    Stenotrophomonas maltophilia is an important nosocomial pathogen. This pathogen has intrinsic or acquired resistance to a number of antibiotics classes. Furthermore, Stenotrophomonas infections have been associat...

    Authors: Eun Jin Kim, Yong Chan Kim, Jin Young Ahn, Su Jin Jeong, Nam Su Ku, Jun Yong Choi, Joon-Sup Yeom and Young Goo Song

    Citation: BMC Infectious Diseases 2019 19:754

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  17. Content type: Research article

    Antimicrobial resistance is one of the most serious public health threats of the twenty-first century. The implementation of AMR surveillance in Zimbabwe is limited. However, data from a private laboratory in ...

    Authors: Marvellous Mhondoro, Nqobile Ndlovu, Donewell Bangure, Tsitsi Juru, Notion Tafara Gombe, Gerald Shambira, Peter Nsubuga and Mufuta Tshimanga

    Citation: BMC Infectious Diseases 2019 19:746

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  18. Content type: Research article

    Due to the similar clinical, lung imaging, and pathological characteristics, talaromycosis is most commonly misdiagnosed as tuberculosis. This study aimed to identify the characteristics of talaromycosis pleur...

    Authors: Ye Qiu, Wen Zeng, Hui Zhang, Xiaoning Zhong, Shudan Tang and Jianquan Zhang

    Citation: BMC Infectious Diseases 2019 19:745

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  19. Content type: Research article

    Multidrug resistant (MDR) enterococci are important nosocomial pathogens causing serious problem in hospitalized patients. The aim of present study was to investigate the frequency of high-level aminoglycoside...

    Authors: Fakhri Haghi, Vahid Lohrasbi and Habib Zeighami

    Citation: BMC Infectious Diseases 2019 19:744

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  20. Content type: Research article

    Trends in antimicrobial resistance help inform infection control efforts. We examined trends in resistance for Enterobacteriaceae and Acinetobacter spp. from 2013 to 2017 in hospitalized US patients.

    Authors: Vikas Gupta, Gang Ye, Melanie Olesky, Kenneth Lawrence, John Murray and Kalvin Yu

    Citation: BMC Infectious Diseases 2019 19:742

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  21. Content type: Study protocol

    Lyme borreliosis (LB) is a tick-borne disease caused by spirochetes belonging to the Borrelia burgdorferi sensu lato species. Due to a variety of clinical manifestations, diagnosing LB can be challenging, and lab...

    Authors: F. R. van de Schoor, M. E. Baarsma, S. A. Gauw, L. A. B. Joosten, B. J. Kullberg, C. C. van den Wijngaard and J. W. Hovius

    Citation: BMC Infectious Diseases 2019 19:732

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  22. Content type: Case report

    Solobacterium moorei, the only species in the genus Solobacterium, is a Gram-positive, non-spore-forming, strict anaerobic, short to long bacillus. It has rarely been documented to cause blood stream infections. ...

    Authors: Wen-Jing Liu, Meng Xiao, Jie Yi, Ying Li, Timothy Kudinha and Ying-Chun Xu

    Citation: BMC Infectious Diseases 2019 19:730

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  23. Content type: Case report

    Coccidioides spp. are dimorphic fungi endemic to Central America, regions of South America and southwestern USA. Two species cause most human disease: Coccidioides immitis (primarily California isolates) and Cocc...

    Authors: Raynell Lang, William Stokes, Jane Lemaire, Andrew Johnson and John Conly

    Citation: BMC Infectious Diseases 2019 19:722

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  24. Content type: Case report

    Clostridium perfringens can cause various infections, including food poisoning, gas gangrene, cellulitis and fasciitis. C. perfringens septicemia is rare, but is a known cause of hemolysis by damaging red blood c...

    Authors: Masahide Sakaue, Koshi Ota, Eriko Nakamura, Masahiko Nitta, Masahiro Oka, Yasuo Oishi, Yohei Sano, Shinya Yonogi and Akira Takasu

    Citation: BMC Infectious Diseases 2019 19:719

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  25. Content type: Research article

    We developed a clinical bedside tool to simultaneously estimate the probabilities of third-generation cephalosporin-resistant Enterobacteriaceae (3GC-R), carbapenem-resistant Enterobacteriaceae (CRE), and mult...

    Authors: Thomas P. Lodise, Nicole Gidaya Bonine, Jiatao Michael Ye, Henry J. Folse and Patrick Gillard

    Citation: BMC Infectious Diseases 2019 19:718

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  26. Content type: Research article

    Coagulase-negative Staphylococci (CoNS) have emerged as a major causative agent of blood-stream infections (BSI). Linezolid (LZD) is currently used for treating glycopeptide and methicillin-resistant staphyloc...

    Authors: Gajanand Mittal, Vasundhra Bhandari, Rajni Gaind, Vandana Rani, Shimpi Chopra, Reetika Dawar, Raman Sardana and P. K. Verma

    Citation: BMC Infectious Diseases 2019 19:717

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  27. Content type: Research article

    Asymptom of invasive candidiasis (IC) and low positive rate of blood culture lead to delay diagnose of neonatal infection. Serum (1,3)-β-D-glucan (BDG) performs well in adult IC, but its use in neonatal IC is ...

    Authors: Junfei Guo, Yongbing Wu, Weiming Lai, Weiming Lu and Xiaoping Mu

    Citation: BMC Infectious Diseases 2019 19:716

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  28. Content type: Research article

    Management of partially-treated, community-acquired bacterial meningitis (PCBM) is commonly compromised by lack of microbiological diagnosis. We aimed to analyze the impact of FilmArray Meningitis-Encephalitis...

    Authors: Yair Mina, Vered Schechner, Michal Savion, Dafna Yahav, Efraim Bilavsky, Nadav Sorek, Haim Ben-Zvi and Amos Adler

    Citation: BMC Infectious Diseases 2019 19:713

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  29. Content type: Research article

    Vancomycin resistant enterococci (VRE) infections are of increasing concern in many hospitalized patients. Patients with cirrhosis are at added risk of infection with VRE, with associated increased risk for co...

    Authors: Melissa Barger, Emily Blodget, Sol Pena, Wendy Mack and Tse-Ling Fong

    Citation: BMC Infectious Diseases 2019 19:711

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  30. Content type: Case report

    Pulmonary Cryptococcosis (PC) is diagnosed with increasing incidence in recent years, but it does not commonly involve the pleural space. Here, we report a HIV-negative case with advanced stage IIIB non-small ...

    Authors: Yuan Zhang, Sean X. Zhang, Julie Trivedi, Adam D. Toll, Julie Brahmer, Russell Hales, Sarah Bonerigo, Mingying Zeng, Huiping Li and Rex C. Yung

    Citation: BMC Infectious Diseases 2019 19:710

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  31. Content type: Case report

    Talaromyces marneffei is a thermally dimorphic fungus endemic in south-east Asia. It predominantly occurs in both immunocompromised and immunosuppressed patients and can be fatal if diagnosis and treatment are...

    Authors: Jiayi Xian, Xiaowen Huang, Qiaofei Li, Xiaoming Peng and Xuebiao Peng

    Citation: BMC Infectious Diseases 2019 19:707

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  32. Content type: Research article

    S. pneumoniae is the leading cause of community-acquired pneumonia in the solid organ transplant recipient (SOTR); nevertheless, the prevalence of colonization and of the colonizing/infecting serotypes has not be...

    Authors: Cristina Roca-Oporto, Tania Cebrero-Cangueiro, María Luisa Gil-Marqués, Gema Labrador-Herrera, Younes Smani, Francisco Manuel González-Roncero, Luis Miguel Marín, Jerónimo Pachón, María Eugenia Pachón-Ibáñez and Elisa Cordero

    Citation: BMC Infectious Diseases 2019 19:697

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  33. Content type: Research article

    Diagnosis is the most strenuous step in the evaluation of neonatal sepsis. No gold standard diagnostic method is available except for blood culture. We aimed to investigate the role of positive and negative ac...

    Authors: Halil Değirmencioğlu, Buse Ozer Bekmez, Turan Derme, Mehmet Yekta Öncel, Fuat Emre Canpolat and Cüneyt Tayman

    Citation: BMC Infectious Diseases 2019 19:695

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  34. Content type: Research article

    Chronic pulmonary aspergillosis (CPA) is an underdiagnosed and misdiagnosed disease and now increasingly recognised. However, the diagnosis of CPA remains challenging. In this study, we aimed to investigate th...

    Authors: Xiuqing Ma, Kaifei Wang, Xin Zhao, Yang Liu, Yanqin Li, Xiaotian Yu, Chunsun Li, David W. Denning and Lixin Xie

    Citation: BMC Infectious Diseases 2019 19:694

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  35. Content type: Research article

    Definitive diagnosis of meningitis is made by analysis of cerebrospinal fluid (CSF) culture or polymerase chain reaction (PCR) obtained from a lumbar puncture (LP), which may take days. A timelier diagnostic c...

    Authors: Michelle Troendle and Alexis Pettigrew

    Citation: BMC Infectious Diseases 2019 19:692

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  36. Content type: Research article

    In most developing countries, puerperal sepsis is treated empirically with broad spectrum antibiotics due to lack of resources for culture and antibiotics susceptibility testing. However, empirical treatment d...

    Authors: Raymond Kiponza, Belinda Balandya, Mtebe V. Majigo and Mecky Matee

    Citation: BMC Infectious Diseases 2019 19:690

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  37. Content type: Case report

    Botrytis species are well known fungal pathogens of various plants but have not been reported as human pathogens, except as allergenic precipitants of asthma and hypersensitivity pneumonitis.

    Authors: Seishu Hashimoto, Eisaku Tanaka, Masakuni Ueyama, Satoru Terada, Takashi Inao, Yusuke Kaji, Takehiro Yasuda, Takashi Hajiro, Tatsuo Nakagawa, Satoshi Noma, Gen Honjo, Yoichiro Kobashi, Noriyuki Abe, Katsuhiko Kamei and Yoshio Taguchi

    Citation: BMC Infectious Diseases 2019 19:684

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  38. Content type: Research article

    Fecal colonization with carbapenem-resistant Enterobacteriaceae (CRE) is a risk factor for bacterial translocation resulting in subsequent endogenous infections. The purpose of this study is to investigate the...

    Authors: Fen Pan, Dongxing Tian, Bingjie Wang, Wantong Zhao, Huihong Qin, Tiandong Zhang and Hong Zhang

    Citation: BMC Infectious Diseases 2019 19:678

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  39. Content type: Research article

    Corynebacterium striatum is an emerging multidrug-resistant (MDR) pathogen associated with immunocompromised and chronically ill patients, as well as nosocomial outbreaks. In this study, we characterized 23 MDR C...

    Authors: Juliana Nunes Ramos, Cassius Souza, Yuri Vieira Faria, Eliane Cristine da Silva, João Flávio Carneiro Veras, Paulo Victor Pereira Baio, Sérgio Henrique Seabra, Lilian de Oliveira Moreira, Raphael Hirata Júnior, Ana Luíza Mattos-Guaraldi and Verônica Viana Vieira

    Citation: BMC Infectious Diseases 2019 19:672

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  40. Content type: Research article

    Scrub typhus is a mite borne zoonosis common in the tropics with no good preventive strategy. Children are also affected leading to considerable morbidity and mortality. We conducted a case control study and a...

    Authors: Winsley Rose, Gagandeep Kang, Valsan Philip Verghese, Sadanandane Candassamy, Prasanna Samuel, John Jude Antony Prakash and Jayaprakash Muliyil

    Citation: BMC Infectious Diseases 2019 19:665

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  41. Content type: Research article

    Several studies have identified predictors of severe infections in antineutrophil cytoplasmic antibody-associated vasculitis (AAV). However, the development of oral candidiasis (OC) as a predictor of subsequen...

    Authors: Makoto Yamaguchi, Takayuki Katsuno, Shiho Iwagaitsu, Hironobu Nobata, Hiroshi Kinashi, Shogo Banno and Yasuhiko Ito

    Citation: BMC Infectious Diseases 2019 19:664

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  42. Content type: Research article

    Community-acquired sepsis is a life-threatening systemic reaction, which starts within ≤72 h of hospital admittance in an infected patient without recent exposure to healthcare risks. Our aim was to evaluate t...

    Authors: Balint Gergely Szabo, Rebeka Kiss, Katalin Szidonia Lenart, Bence Marosi, Eszter Vad, Botond Lakatos and Eszter Ostorhazi

    Citation: BMC Infectious Diseases 2019 19:584

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  43. Content type: Case report

    Rapid diagnosis and appropriate treatment is imperative in bacterial sepsis due increasing risk of mortality with every hour without appropriate antibiotic therapy. Atypical infections with fastidious organism...

    Authors: Seweryn Bialasiewicz, Tania P. S. Duarte, Son H. Nguyen, Vichitra Sukumaran, Alexandra Stewart, Sally Appleton, Miranda E. Pitt, Arnold Bainomugisa, Amy V. Jennison, Rikki Graham, Lachlan J. M. Coin and Krispin Hajkowicz

    Citation: BMC Infectious Diseases 2019 19:660

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  44. Content type: Research article

    Cervicofacial necrotizing fasciitis (NF) is a rare life-threatening infection in the head and neck region that characteristically spreads along the fascial planes to involve subcutaneous tissues, fascia and fa...

    Authors: Arnold A. Mtenga, Boniphace M. Kalyanyama, Sira S. Owibingire, Karpal S. Sohal and Elison N.M. Simon

    Citation: BMC Infectious Diseases 2019 19:642

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  45. Content type: Research article

    In hospitalised patients with diarrhoea a positive campylobacter stool Polymerase Chain Reaction (PCR) test with negative culture results as well as Enteropathogenic Escherichia coli (EPEC) positive stool PCRs, c...

    Authors: Jan-Erik Berdal, Benoit Follin-Arbelet and Jørgen Vildershøj Bjørnholt

    Citation: BMC Infectious Diseases 2019 19:630

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