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Table 3 Disease severity and outcomes for patients by whether they received effective empirical antibiotic treatment

From: Prevalence of and risk factor for community-onset third-generation cephalosporin-resistant Escherichia coli bacteremia at a medical center in Taiwan

Disease severity / Outcomes Community-onset bacteremia Community-acquired bacteremia Urosepsis
Effective Tx (n = 564) Ineffective Tx (n = 112) P value Effective Tx (n = 267) Ineffective Tx (n = 36) P value Effective Tx (n = 281) Ineffective Tx (n = 54) P value
Charlson comorbidity index, median (range) 2 (0–11) 2 (0–13) 0.587b 1 (0–10) 1 (0–6) 0.294b 2 (0–11) 2 (0–11) 0.413b
Shock upon presentation (%) 94 (16.7) 13 (11.6) 0.180 19 (7.1) 1 (2.8) 0.487c 35 (12.5) 3 (5.6) 0.166c
Death within 14 days (%) 54 (9.6) 10 (8.9) 0.831 6(2.3) 0(0) 0.364 13(4.6) 2(3.7) 0.764
Hospital stay, median days (range)a 14 (3–159) 17 (6–80) 0.005b 12 (3–44) 16 (6–52) 0.002b 14 (3–159) 15 (7–80) 0.039b
  1. aExcluding patients who died during hospitalization (Among patients with community-onset bacteremia, only 413 patients who received effective empirical antibiotic treatment and 83 patients who received ineffective empirical antibiotic treatment were analyzed. In community-acquired bacteremia group, only 191 patients who received effective empirical antibiotic treatment and 28 patients who received ineffective empirical antibiotic treatment were analyzed, whereas in urosepsis group, only 223 patients who received effective empirical antibiotics and 41 patients who received ineffective empirical antibiotic treatment were analyzed)
  2. bCompared by Mann–Whitney U test
  3. cCompared by Fisher’s exact test
  4. Abbreviation: Tx empirical antibiotics treatment