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Table 2 Demographic and clinical HIV patients and control group characteristics

From: Alterations in bacterial communities, SCFA and biomarkers in an elderly HIV-positive and HIV-negative population in western Mexico

  HIV-negative (n = 18) HIV-positive (n = 20) p value
Age (years) 68 ± 5 57 ± 5 p < 0.05a
Gender
 Male 11 (61.1%) 16 (80.0%) p = 0.209b
 Female 7 (38.9%) 4 (20.0%)  
CD4 T cells count; cell/μL 409 (IQR: 279,744)
CD4 nadir T cells count; cell/μL 74 (IQR: 39,220)
CD4/CD8 ratio 0.71 (IQR: 0.37,1.16)
HIV-1 viral load; copies/μL 34 ± 9.4
Tobacco Use:
 No risk 3 (16.7%) 5 (25.0%) p = 0.697b
 Moderate 4 (22.2%) 1 (5.0%) p = 0.170b
 Moderate/intense 2 (11.1%) 1 (5.0%) p = 0.595b
 High 1 (5.6%) 1 (5.0%) p = 1.000b
 No consumption 8 (44.4%) 12 (60.0%) p = 0.332b
Alcohol use
 Yes 10 (55.6%) 5 (25.0%) p < 0.05c
 No 8 (44.4%) 15 (75.0%)  
Drugs antecedent
 Yes 1 (5.6%) 13 (65.0%) p < 0.05b
 No 17 (94.4%) 7 (35.0%)  
Body Mass Index
 Normal 8 (44.4%) 11 (55.0%) p = 0.513c
 Overweight 10 (55.6%) 9 (45.0%)  
Waist diameter
Men    p = 1.000c
 <  90 cm 6 (54.5%) 8 (50.0%)  
 ≥ 90 cm 5 (45.5%) 8 (50.0%)  
Women    p = 1.000b
 <  80 cm 2 (28.6%) 1 (25.0%)  
 ≥ 80 cm 5 (71.4%) 3 (75.0%)  
Hypertension
 Yes 1 (5.6%) 2 (10.0%) p = 1.000b
 No 17 (94.4%) 18 (90.0%)  
Hypercholesterolemia
 Yes 8 (55.6%) 11 (55.0%) p = 0.513c
 No 10 (44.4%) 8 (40.0%)  
 Unknown 1 (5.0%)  
Depression PHQ-9
 Yes 1 (5.6%) 1 (5.0%) p = 1.000b
 No 17 (94.4%) 19 (95.0%)  
IBS QoL 2.8 ± 1.8 2.9 ± 1.8 p = 0.860a
VACS 15.9 ± 9.3  
Fragility score
 No-fragility 9 (50) 5 (25.0) p = 0.179c
 Pre-fragility 4 (22.2) 14 (70.0) p < 0.05c
 Fragility 5 (27.8) 1 (5.0) p = 0.467c
Albumin; g/dL 4.1 ± 0.4 4.3 ± 0.5 p = 0.180a
hs-CRP; μg/mL 3.5 ± 2.19 2.12 ± 2.05 p < 0.05a
sCD14; ng/mL 1131.0 (887.1–1559.3) 819.7 (739.6–1030.2) p < 0.05d
SCFAs; mM
 Total 46.17 ± 12.9 57.12 ± 13.49 p < 0.05a
 Acetic acid 3.86 ± 3.79 1.52 ± 1.9 p < 0.05a
 Propionic acid 41.07 ± 15.62 55.05 ± 14.25 p < 0.05a
 Butyric acid 0.99 ± 1.55 0.32 ± 0.41 p < 0.05a
Firmicutes/Bacteroidetes ratio 1.7 ± 0.62 2.37 ± 0.92 p < 0.05a
  1. aStudent’s t-test, bFisher exact, cChi square, dU of Mann-Whitney test