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Table 1 Clinical characteristics of the AIDS-PCP patients between survivors and non-survivors

From: Activation of the kynurenine pathway is associated with poor outcome in Pneumocystis pneumonia patients infected with HIV: results of 2 months cohort study

  Survivors (n = 38) Non-survivors (n = 11) P-value
Sex, M/F 37/1 11/0 NA
Age, yr 40.97 ± 14.29 43.55 ± 16.48 0.684
Body mass index 19.69 ± 2.648 20.90 ± 2.43 0.274
CD4+ cell count, cells/mm3(ul) 59.28 ± 30.38 47.15 ± 28.71 0.387
D-dimer 1314.34 ± 1697.91 5427.91 ± 8050.52 0.010
Albumin 33.05 ± 5.26 25.37 ± 5.99 0.001
CRP 39.88 ± 148.75 91.74 ± 56.27 0.007
ESR 60.23 ± 25.96 66.00 ± 30.17 0.615
P/F ratio, mmHg 398.34 ± 135.17 318.33 ± 106.62 0.144
LDH 339.55 ± 148.75 543.38 ± 328.44 0.045
Kynurenine 2.93 ± 2.19 4.32 ± 3.56 0.051
Tryptophan 15.48 ± 3.13 15.54 ± 3.66 0.952
Kyn/Trp (mM/M) 169.05 ± 72.40 275.91 ± 132.03 0.002
PaO2/FiO2 ≤ 300 mmHg, No. (%) 9 (9/38) 9 (9/11) 0.001
Patients receiving ART, No. (%) 6 (6/38) 4 (4/11) 0.201
Treatment for PCP 38 11 NA
  1. Data are expressed as mean and SD