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Table 2 Predictors of HIV-1 DNA Level at Week 48

From: The effects of antiretroviral therapy initiation time on HIV reservoir size in Chinese chronically HIV infected patients: a prospective, multi-site cohort study

  HIV-1 DNA at week 48 (Log10 copies/106PBMCs)
Predictor Estimate 95% CI P Value
Univariate Model
Early ART Initiation −0.309 − 0.408 to − 0.210 0.001
Age (years) + 0.007 + 0.002 to + 0.013 0.01
Baseline HIV-1 RNA (log10 copies/mL) + 0.345 + 0.268 to + 0.423 0.001
Baseline HIV-1 DNA (log10 copies /106PBMCs) + 0.696 + 0.633 to + 0.759 0.001
Baseline CD4/CD8 ratio −0.643 − 0.955 to − 0.332 0.001
Model with Early ART initiation, age, baseline HIV-1 RNA, baseline HIV-1 DNA and baseline CD4/CD8 ratio
Early ART initiation −0.092 −0.173 to − 0.011 0.025
Age(years) + 0.002 −0.002 to + 0.006 0.339
Baseline HIV-1 RNA (log10 copies/mL) + 0.026 −0.061 to + 0.114 0.553
Baseline HIV-1DNA (log10 copies /106PBMCs) + 0.631 + 0.545 to + 0.717 0.001
Baseline CD4/CD8 ratio −0.309 −0.448 to − 0.169 0.001