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Table 5 The MICs of fluoroquinolones and gyrase mutations for 9 isolates with moxifloxacin resistance

From: Epidemiology of Clostridium difficile infection in hospitalized adults and the first isolation of C. difficile PCR ribotype 027 in central China

Number of strains MIC (ug/ml) Gyrase mutations
Ciprofloxacin Levofloxacin Moxifloxacin GyrA GyrB
TCD10 0.125 128 16 Thr82Ile  
TCD17 > 128 > 128 32 Thr82Ile  
TCD 27 64 > 128 8 Thr82Ile  
TCD 28 32 16 16 Thr82Ile  
TCD 42 128 > 128 32 Thr82Ile  
TCD 53 8 16 8 Thr82Ile  
TCD 54 64 64 32 Thr82Ile  
TCD 58 128 > 128 32 Thr82Ile Ser366Ala
TCD 59 64 64 32 Thr82Ile