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Table 6 Prognostic factors associated with prolonged time (≥7 days) taken for temperature normalization in PLA patients

From: Comparison of clinical characteristics and outcomes of pyogenic liver abscess patients < 65 years of age versus ≥ 65 years of age

Variable (N = 332) Univariate analysis Multivariate analysis
<  7 days N = 174 ≥ 7 days N = 158 P value OR (95% CI) P value
Age (years; median, range) 57(20–89) 59(18–84) 0.385   
Gender (Male/Female) 108/66 79/79 0.027 1.767(1.017–3.070) 0.012
Etiologies (n, %)
 Biliary source 64(36.8%) 43(27.2%) 0.063   
 Portal vein seeding, bowel and/or pelvic pathology 13(7.5%) 16(10.1%) 0.392   
 Hepatic artery seeding 6(3.4%) 12(7.6%) 0.162   
 Direct extension 18(10.3%) 21(13.3%) 0.405   
 Trauma to the liver 7(4.0%) 5(3.2%) 0.676   
 Cryptogenic infection 65(37.4%) 61(38.6%) 0.814   
Comorbidities (n, %)
 Smoking 52(29.9%) 38(24.1%) 0.232   
 Drinking 38(21.8%) 18(11.4%) 0.011 2.849(1.262–6.430) 0.012
 Hypertension 40(23.0%) 29(18.4%) 0.299   
 Diabetes mellitus 58(33.3%) 48(30.4%) 0.564   
 Hepatobiliary malignant diseases 19(10.9%) 21(13.3%) 0.507   
 Cholelithiasis 74(42.5%) 49(31.0%) 0.052   
 Cirrhosis 10(5.7%) 4(2.5%) 0.145   
 Viral hepatitis 14(8.0%) 9(5.7%) 0.400   
Surgery history
 Abdominal surgery history 87(50.0%) 68(43.0%) 0.204   
  Hepatobiliary surgery 74(42.5%) 55(34.8%) 0.150   
  Other surgery 13(8.5%) 13(8.2%) 0.798