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Table 3 The genotype and allele frequencies of rs3764880 in the second sample

From: Association of TLR8 and TLR9 polymorphisms with tuberculosis in a Chinese Han population: a case-control study

Genotypes and allele frequencies Cases, n (%) Controls, n (%) OR (95%CI) P value
PTB and LTBI
 Males
  TLR8 rs3764880 major allele G 84 (79.2) 84 (88.4) 1 Reference
  TLR8 rs3764880 minor allele A 22 (20.8) 11 (11.6) 1.92 (0.85–4.32) 0.12
 Females
  TLR8 rs3764880 GG 65 (63.7) 71 (67.6) 1 Reference
  TLR8 rs3764880 GA 28 (27.5) 31 (29.5) 1.08 (0.56–2.09) 0.83
  TLR8 rs3764880 AA 9 (8.8) 3 (2.9) 4.81 (1.11–20.85) 0.04
  TLR8 rs3764880 major allele G 158 (77.5) 173 (82.4) 1 Reference
  TLR8 rs3764880 minor allele A 46 (22.5) 37 (17.6) 1.56 (0.93–2.62) 0.09
LTBI and HC
 Males
  TLR8 rs3764880 major allele G 84 (88.4) 76 (82.6) 1 Reference
  TLR8 rs3764880 minor allele A 11 (11.6) 16 (17.4) 0.53 (0.23–1.25) 0.15
 Females
  TLR8 rs3764880 GG 71 (67.6) 70 (63.1) 1 Reference
  TLR8 rs3764880 GA 31 (29.5) 36 (32.4) 0.85 (0.47–1.52) 0.58
  TLR8 rs3764880 AA 3 (2.9) 5 (4.5) 0.64 (0.15–2.84) 0.56
  TLR8 rs3764880 major allele G 173 (82.4) 176 (79.3) 1 Reference
  TLR8 rs3764880 minor allele A 37 (17.6) 46 (20.7) 0.83 (0.51–1.34) 0.44
  1. Abbreviations: PTB pulmonary tuberculosis, LTBI latent tuberculosis infection, HC healthy control, OR odds ratio, CI confidence interval. P value adjusted for age