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Table 4 Selected virulence associated genes found on the FHI-NMBU-03 chromosome by nBLAST

From: High frequency of hybrid Escherichia coli strains with combined Intestinal Pathogenic Escherichia coli (IPEC) and Extraintestinal Pathogenic Escherichia coli (ExPEC) virulence factors isolated from human faecal samples

Gene name (FHI-NMBU-03 chromosome) Comment Associated pathovar % identity Cover. BLAST sequence
aatB Autotransporter adhesin and virulence factor of avian pathogenic Escherichia coli. APEC 98.43 1017 / 1017 JX402062
herA Archaeal bi-polar DNA helicase Unknown 99.47 1686 / 1686 NZ_NLRN01000019
aslA Arylsulfatase gene ExPEC (Invasive K1 strains) 98.55 1656 / 1656 CU928163
aufC Fimbrial usher protein gene UPEC 99.50 2595 / 2595 KE702411
cesAB Enteropathogenic Escherichia coli chaperone for the type-III translocator proteins EPEC/STEC 100.00 324 / 324 FM986651
cesD2 A second chaperone for the type III secretion translocator protein EspD EPEC/STEC 98.28 407 / 408 NC013364
cesT A bivalent enteropathogenic Escherichia coli chaperone required for translocation of both Tir and Map EPEC/STEC 100.00 471 / 471 LT903847
chuA E.coli hemeutilization protein A gene ExPEC 99.65 1983 / 1983 LT827011
cif Type III secreted effector EPEC/STEC 100.00 849 / 849 AF497476
csgA Major curlin subunit Several 99.56 459 / 459 CP023388
csgB Minor curlin subunit Several 99.56 456 / 456 CP027060
csgE Curli production assembly/transport component Several 98.70 386 / 390 NC_011750
csgF Curli production assembly/transport component Several 98.08 417 / 417 NC_011750
csgG Curli production assembly/transport component Several 97.72 834 / 834 CP003034
cvaA Colicin V secretion protein gene Several 100.00 1242 / 1242 GG773553
Death on curing RelE/ParE family toxin gene Component of Toxin-antitoxin (TA) system Several 100.00 272 / 276 CP023388
eae (subtype Beta2) Intimin - Necessary for the production of attaching and effacing lesions on tissue culture cells EPEC/STEC 100.00 2820 / 2820 AB647493
ecpA Common pilus major fimbrillin subunit Several 98.47 588 / 588 BA000007
ecpD Fimbria adhesin of the E.coli common pilus Several 99.64 1644 / 1644 CP019777
elfC Putative fimbrial usher protein Several 99.73 2595 / 2595 CP021288
entA Enterobactin biosynthesis gene Several 96.12 747 / 747 CP027060
entE Enterobactin biosynthesis gene Several 95.65 1611 / 1611 CP027060
entH Enterobactin biosynthesis gene Several 94.93 414 / 414 CP027060
escC Outer membrane secretin EPEC/STEC 91.68 1539 / 1539 AP010958
escD Type III secretion system inner membrane ring protein EPEC/STEC 99.10 1221 / 1221 BA000007
escF Type III secretion system needle major subunit EPEC/STEC 100.00 222 / 222 NC_002695
escJ Required for the formation of the type III Secretion Apparatus EPEC/STEC 91.62 573 / 573 AP010958
escN Type III secretion ATPase EPEC/STEC 100.00 1341 / 1341 BA000007
escR Type III secretion system export apparatus protein gene EPEC/STEC 99.69 654 / 654 BA000007
escS Type III secretion system export apparatus protein gene EPEC/STEC 100.00 270 / 270 BA000007
escT Type III secretion system export apparatus protein gene EPEC/STEC 99.61 777 / 777 BA000007
escU Type III secretion system LEE export apparatus switch protein gene EPEC/STEC 96.15 1038 / 1038 AP010958
escV Translocase of the type III secretion system EPEC/STEC 99.70 2028 / 2028 BA000007
espA Type III secretions system gene EPEC/STEC 100.00 573 / 573 AJ225016
espG Type III secretion system effector, which localize to the Golgi apparatus and disrupt its architecture EPEC/STEC 98.41 1197 / 1197 BA000007
etgA Lytic transglycosylase EPEC/STEC 100.00 459 / 459 FM986650
fdeC Mediates E. coli adhesion to mammalian cells and extracellular matrix ExPEC/STEC 97.86 4251 / 4251 CP019777
sfaH S-fimbrial protein subunit gene ExPEC 98.56 903 / 903 KT444704
flgD Flagellar basal body rod modification protein gene Several 96.55 696 / 696 CP027060
flgM Negative regulator of flagellin synthesis Several 98.97 290 / 294 CP028192
fmlA Major F9-fimbrial subunit ExPEC/IPEC 96.81 564 / 564 BA000007
fyuA Ferric yersiniabactin uptake receptor ExPEC 99.51 2022 / 2022 CP016828
gad (1) Glutamate decarboxylase gene Several 99.64 1401 / 1401 CP001671
gad (2) Glutamate decarboxylase gene Several 99.79 1401 / 1401 FM180568
grlA Global regulator of LEE activator EPEC/STEC 97.56 409 / 414 AP010958
gtrA Type IV O-antigen modification gene (Shigella flexneri) Unknown 90.08 363 / 363 AF288197
hbp Hemoglobin-binding protease hbp autotransporter gene ExPEC 99.95 4131 / 4131 CP009072
hlyIII Gene encoding inner membrane protein, hemolysin III family ExPEC/IPEC 98.41 690 / 690 CP003034
ibeA Invasion protein gene NMEC/APEC/AIEC 98.61 1371 / 1371 CP001855
ibeB Invasion protein gene Several 98.55 1383 / 1383 AF094824
ibeC/yijP/cptA Invasion protein gene Several 99.77 1734 / 1734 CP019777
irp1 HMWP1 nonribosomal peptide/polyketide synthase ExPEC 99.65 9492 / 9492 CU928163
irp2 HMWP2 Yersiniabactin biosynthetic protein ExPEC 98.85 6106 / 6108 CP006834
ler Negative autoregulator of the LEE1 operon EPEC/STEC 99.49 390 / 390 BA000007
malX Escherichia coli pathogenicity island-marker ExPEC 98.61 1581 / 1581 AF003742
MAP LEE effector protein gene EPEC/STEC 97.06 612 / 612 LC053401
MBL-fold metallo hydrolase gene Putative phylogroup B2 specific marker ExPEC 99.52 1044 / 1044 CP023388
mdtH Multidrug resistance protein gene Several 99.83 1209 / 1209 CP019777
mpc Type III secretion system regulator gene EPEC/STEC 92.09 354 / 354 AP010953
mviM Putative virulence factor Several 98.70 924 / 924 CU928164
nleA a Non-LEE encoded effector A EPEC/STEC 99.84 1239 / 1239 AB303062
nleB Non-LEE encoded effector B EPEC/STEC 100.00 981 / 981 AB303062
nleC-like gene T3SS secreted effector NleC-like protein gene EPEC/STEC 100.00 264 / 264 CYEL01000033
nleG Non-LEE encoded effector G EPEC/STEC 100.00 576 / 576 AB303062
nleH Non-LEE encoded effector H EPEC/STEC 99.75 812 / 812 AP010958
usp/putative colicin Uropathogenic specific protein gene UPEC 97.14 1782 / 1782 CU651637
sepL Secretion switching protein gene EPEC/STEC 94.93 1046 / 1056 BA000007
sepQ T3SS structure protein EPEC/STEC 95.53 918 / 918 CP003109
sinH Intimin-like inverse autotransporter ExPEC 100.00 2178 / 2178 NZ_NMHI01000013
stcD Putative fimbrial-like adhesin protein gene IPEC 99.71 1035 / 1035 NC_018658
stfD Fimbrial protein gene Unknown 100.00 753 / 753 LOFW01000008
tir Translocated intimin receptor protein gene EPEC/STEC 99.88 1650 / 1650 DQ206455
xhlA Xenorhabdus nematophila haemolysin Unknown 99.73 372 / 372 LDCR01000046
ybtA Yersiniabactin transcriptional regulator ExPEC 99.79 960 / 960 CP028714
ydeR Fimbrial-like protein gene Several 98.41 504 / 504 CU928163
yfcV Major subunit of a putative chaperone-usher fimbria ExPEC 97.18 567 / 567 NC_011750
  1. aFrameshifted