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Table 2 Associations of epidemiological factors to prevalence of Streptococcus pneumoniae in middle ear fluid in children with AOM - univariate and multivariate analysis

From: Resistant Streptococcus pneumoniae strains in children with acute otitis media– high risk of persistent colonization after treatment

Characteristics Univariate analysis Multivariate model
OR (95% CI) P value OR (95% CI) P value
Age (yr) 0.8 (0.61–1.06) 0.13   
Male sex 1.6 (0.86–3.03) 0.14   
Sibling possessing 0.96 (0.53–1.72) 0.88   
DCC/school attendance 0.93 (0.50–1.73) 0.83   
Bilaterality 1.38 (0.76–2.52) 0.29   
Category of AOM:TF/R 1.28 (0.67–2.42) 0.46 0.05 (0.01–0.17) 0.062
CRP (mg/L) 1.05 (0.97–1.14) 0.23 1.12 (1.01–1.25) 0.039*
WBC (G/L) 1.21 (1.07–1.36) 0.002* 1.22 (1.05–1.42) 0.009*
Ongoing antibiotic therapy at the admission to hospital 0.54 (0.24–1.21) 0.14 0.07 (0.006–0.87) 0.038*
Antipneumococcal vaccination 0.42 (0.14–1.2) 0.10 0.059 (0.002–1.57) 0.091
  1. *Statistic significance; R recurrent AOM, TF treatment failure AOM, N new case AOM, DCC day care center, CRP C-reactive protein, WBC white blood cells