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Table 4 Observed and expected PWA deaths, with corresponding SMRs, by mode of HIV transmission. Italy, 2006-2011

From: Excess mortality related to circulatory system diseases and diabetes mellitus among Italian AIDS patients vs. non-AIDS population: a population-based cohort study using the multiple causes-of-death approach

Conditions present at deatha (ICD-10 codes) Mode of HIV transmissionc
Injecting drug use (473 deaths, 4048 person-years) Sexual intercoursed (669 deaths, 9302 person-years)
Obs./Exp. SMR (95% CI) Obs./Exp. SMR (95% CI)
Circulatory system diseases (I00–I99) a,b 79/2.5 31.8 (25.2–39.6) 108/12.2 8.9 (7.3–10.7)
 Hypertension (I10–I15) 6/0.5 12.6 (4.6–27.4) 16/2.9 5.6 (3.2–9.1)
 Ischemic heart diseases (I20–I25) 10/1.0 10.5 (5.0–19.3) 27/4.9 5.5 (3.7–8.1)
  Acute myocardial infarction (I21) 5/0.7 7.6 (2.5–17.7) 11/2.8 4.0 (2.0–7.1)
  Chronic ischemic heart disease (I25) 4/0.4 9.1 (2.5–23.4) 17/2.8 6.0 (3.5–9.6)
 Other forms of heart diseases (I30–I52)b 34/1.0 33.9 (23.5–47.4) 45/5.0 9.0 (6.6–12.1)
 Cerebrovascular diseases (I60–I69) 16/0.4 37.0 (21.2–60.1) 22/2.4 9.2 (5.7–13.9)
  Stroke (I61, I63–I64) 8/0.3 26.5 (11.4–52.2) 13/1.5 8.4 (4.5–14.3)
Diabetes mellitus (E10–E14) 16/0.4 39.8 (22.8–64.7) 26/2.8 9.3 (6.1–13.7)
  1. PWA people with AIDS, SMR sex and age-standardized mortality ratio, CI confidence interval; obs./exp.: observed/expected deaths
  2. a Conditions reported in any field of death certificates. Conditions reported in the same death certificate within the same ICD-10 group were counted only once; group of conditions with less than 10 observed cases among total PWA are not shown
  3. bBut I46 (i.e., cardiac arrest)
  4. cThe sum does not add up to total PWA because “other HIV transmission modes” were not reported
  5. dIncluding both male-to-male and heterosexual intercourse