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Table 1 Patient baseline characteristics

From: Impact of matrix-assisted laser desorption/ionization time of flight mass spectrometric evaluation on the clinical outcomes of patients with bacteremia and fungemia in clinical settings lacking an antimicrobial stewardship program: a pre-post quasi experimental study

Baseline Characteristics Conventional period n = 302 (%) MALDI-TOF period n = 254 (%) P Value†
Age (years), mean ± SD 63.5 ± 12.3 61.6 ± 13.9 0.088
Female 114 (37.7) 136 (53.5) < 0.001
Underlying disease
 Solid tumor 169 (56.0) 133 (52.4) 0.396
 Hematologic malignancy 27 (8.9) 20 (7.9) 0.653
 Cardiovascular disease 54 (17.9) 54 (21.3) 0.316
 Cerebrovascular disease 30 (9.9) 35 (13.8) 0.160
 Chronic lung disease 7 (2.3) 9 (3.5) 0.389
 Chronic liver disease 44 (14.6) 26 (10.2) 0.125
 Chronic kidney disease 42 (13.9) 34 (13.4) 0.858
 Transplantation 16 (5.3) 11 (4.3) 0.597
Charlson score, median (IQR) 6 (2–7) 6 (2–7) 0.505
Clinical conditions
 Prior Chemotherapy within 30 days 81 (26.8) 63 (24.8) 0.588
 Neutropenia (ANC < 500 cells/μL) 26 (8.6) 19 (7.5) 0.627
 ICU stay 51 (16.9) 47 (18.5) 0.618
 SOFA score, mean ± SD 3.7 ± 3.6 4.2 ± 3.6 0.110
Acquisition of BSI
 Community acquired 190 (62.9) 165 (65.0) 0.617
 Hospital acquired 112 (37.1) 89 (35.0) 0.617
Source of BSI
 Urinary tract 61 (20.2) 57 (22.4) 0.519
 Respiratory tract 38 (12.6) 23 (9.1) 0.185
 Biliary tract 73 (24.2) 63 (24.8) 0.863
 Abdomen except biliary tract 29 (9.6) 23 (9.1) 0.825
 Central venous catheter 32 (10.6) 27 (10.6) 0.990
 Foreign device 5 (1.7) 2 (0.8) 0.462
 SSTI/BJI 20 (6.6) 10 (3.9) 0.163
 Infective endocarditis 6 (2.0) 4 (1.6) 0.761
 Primary Unknown 38 (12.6) 45 (17.7) 0.091
  1. *Abbreviations: MALDI-TOF matrix-assisted laser desorption/ionization time-of-flight, IQR interquartile range, ANC absolute neutrophil count, ICU intensive care unit, SOFA score sepsis related organ failure assessment score, BSI bloodstream infection, SSTI skin and soft tissue infection, BJI bone and joint infection
  2. P-values were calculated using the chi-square or Fisher’s exact test for categorical variables and Student’s t-test for continuous variables