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Table 3 Impact of precise co-morbidities on 28-day mortality

From: Progression into sepsis: an individualized process varying by the interaction of comorbidities with the underlying infection

Co-morbidity Odds ratio 95% confidence intervals p-value
Patients with acute pyelonephritis
 Chronic heart failure 2.54 1.82–3.55 < 0.0001
 Chronic renal disease 1.71 1.13–2.60 0.011
 Non-metastatic solid tumor malignancy 2.13 1.44–3.17 < 0.0001
 Corticosteroid intake 2.05 1.09–3.84 0.024
 Stroke 2.97 2.12–4.17 < 0.0001
 Dementia 2.18 1.51–3.15 < 0.0001
Patients with community-acquired pneumonia
 Coronary heart disease 1.87 1.30–2.69 0.001
 Dementia 2.20 1.53–3.17 < 0.0001
Patients with intraabdominal infections
 Type 2 diabetes mellitus 1.84 1.16–2.93 0.010
 Chronic renal disease 2.67 1.12–6.35 0.026
 Non-metastatic solid tumor malignancy 3.03 1.79–5.13 < 0.0001
 Atrial fibrillation 2.23 1.11–4.48 0.024
 Dementia 3.69 1.87–7.25 < 0.0001
 Liver cirrhosis 4.59 1.20–17.51 0.025
Patients with primary bacteremia
 Dementia 3.87 1.65–9.12 0.002
  1. Only variables remaining significant after the final step of logistic forward conditional regression analysis are included