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Table 2 Comparison of characteristics of patients with spondylodiscitis caused by coagulase-negative staphylococcus (CoNS) and caused by Staphylococcus aureus

From: Characteristics of spontaneous coagulase-negative staphylococcal spondylodiscitis: a retrospective comparative study versus Staphylococcus aureus spondylodiscitis

  1: S.aureus n = 30 2: CoNS total n = 26 3: CoNS confirmed n = 15 4:CoNS probable n = 11 p 1 vs 2 p 1 vs 3 p 3 vs 4
Age (mean [95% CI]) 61 [56; 67] 70 [66; 75] 71[64; 78] 70 [64; 76] 0.01 0.02 0.6
Male n (%) 21 (70) 19 (73) 11 (73) 8 (73) 0.8 0.8 1
Site n (%)      0.7 0.8 0.3
 - Cervical 3 (10) 3 (12) 1 (7) 2 (18)    
 - Thoracic 7 (23) 7 (27) 3 (20) 4 (36)   
 - Lumbar 18 (60) 16 (62) 11 (73) 5 (45)   
Symptoms for more than 15 days n (%) 18 (60) 23 (88) 13 (87) 10 (91) 0.01 0.07 0.7
Duration (d) of hospitalization (median [95% CI]) 28 [23.4;. 32.6] 21.5 [16.5; 26.4] 23.6 [15.8; 31.4] 18.5 [12.4; 24.7] 0.05 0.3 0.3
Temperature > 38 °C n (%) 15 (50) 5 (19) 5 (33) 0 (0) 0.01 0.3 0.05
Presence of risk factors n (%) 14 (47) 15 (58) 9 (60) 6 (55) 0.4 0.4 0.8
Cancer n (%) 0 (0) 4 (15) 3(20) 1 (9) 0.04 0.03 0.6
Diabetes n (%) 9 (30) 8 (31) 5 (33) 3 (27) 0.9 0.8 1
Entry site
 -Cutaneous n (%) 9 (30) 6 (23) 2 (13) 4 (36) 0.5 0.3 0.13
 -Catheter n (%) 1 (3) 5 (19) 3 (20) 2(18) 0.08 0.1 1
Blood cultures n (%) 20 (71) 13 (50) 12 (80) 1 (9) 0.1 0.5 0.001
Percutaneous needle biopsy made n (%) 11 (37) 19 (73) 9 (60) 10 (90) 0.008 0.1 0.07
Positive percutaneous needle biopsy n (%) 9 (82) 16 (84) 7 (78) 9 (90) 0.8 0.8 0.46
Leukocytes (G/L) (mean [95% CI]) 9.9 [8.4; 11.4] 7.6 [6.6; 8.6] 8.3 [6.8; 9.7] 6.7 [5.2; 8.3] 0.01 0.5 0.1
PMN (G/L) (mean [95% CI]) 7.5 [6.0; 9.0] 5.6 [4.6; 6.6] 6.3 [4.9; 7.7] 4.6 [3.2; 6.0] 0.04 0.1 0.07
ESR < 30 at 1 h n (%) 0 (0) 5 (23) 2(15) 3(33) 0.01 0.1 0.3
CRP > 10 mg/L n (%) 30 (100) 20 (77) 12(80) 8(73) 0.005 0.02 0.6
Antibiotic therapy duration (d) (median [95% CI]) 91.5 [84.4; 98.7] 82.6 [74.5; 90.6] 75.6 [63.7; 87.5] 93.0 [86.2; 99.8] 0.1 0.05 0.09
Sensitivity to methicillin n (%) 24(80) 16 (61) 10(67) 6(55) 0.1 0.2 0.7
  1. PMN polymorphonuclear leucocytes, ESR erythrocyte sedimentation rate, CRP C-reactive protein