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Table 2 The relationship between expression of specific var subclasses, IE surface antibodies (αIE) and parasite multiplication rate (PMR)

From: Plasmodium falciparum malaria parasite var gene expression is modified by host antibodies: longitudinal evidence from controlled infections of Kenyan adults with varying natural exposure

  αIE PMR Parasitemia
rho p rho p rho p
Transcript quantity (individual primers)
 gpA1 −0.62 0.0006* 0.44 0.02 0.08 0.7
 gpA3 −0.38 0.05 0.38 0.049 0.14 0.5
 gpA4 −0.37 0.05 −0.13 0.5 −0.22 0.3
 dc13 0.07 0.7 −0.08 0.7 −0.03 0.9
 dc8-1 −0.39 0.045 0.60 0.001* 0.18 0.4
 dc8-2 −0.53 0.004* 0.43 0.03 0.13 0.5
 dc8-3 −0.53 0.005* 0.13 0.5 −0.24 0.22
 dc8-4 −0.56 0.003* 0.22 0.3 0.14 0.5
 b1 −0.03 0.9 0.17 0.4 0.45 0.02
 c1 −0.12 0.6 −0.34 0.08 −0.07 0.7
Transcript quantity (medians)
 gpA_median −0.50 0.008 0.39 0.045 0.06 0.8
 dc8_median −0.57 0.002 0.44 0.02 0.05 0.8
Proportional expression
 gpA_prop −0.70 0.0001* 0.52 0.006* −0.04 0.9
 dc8_prop −0.47 0.01 0.42 0.03 −0.08 0.7
 dc13_prop 0.11 0.6 −0.11 0.6 −0.05 0.8
 b1_prop 0.31 0.1 −0.06 0.8 0.38 0.05
 c1_prop 0.25 0.2 −0.51 0.006* −0.15 0.4
Non-overlapping proportional expression
 gpA_prop2 −0.63 0.0005* 0.50 0.007* −0.14 0.5
 b1_prop2 0.33 0.1 −0.02 0.91 0.36 0.06
 c1_prop2 0.28 0.2 −0.50 0.008* −0.15 0.4
  1. Shown is the Spearman’s correlation coefficient and uncorrected p-value. The names of the primers listed in Table 1 were used to represent the var subclasses. *Indicate p-value that was significant after Bonferroni correction for multiple comparisons (10, 5 and 3 comparisons for the transcript quantity, proportional expression and non-overlapping proportional expression respectively). PMR parasite multiplication rate, αIE antibodies to IE