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Table 4 Study 2. Comparison between two groups of infants (≤2y/o) diagnosed of RSV infection

From: SOFIA®RSV: prospective laboratory evaluation and implementation of a rapid diagnostic test in a pediatric emergency ward

  Group 2 Delayed RSV diagnosis at the laboratory (n = 47) Group 3 RSV diagnosis at POCT (n = 160) P-value % of infants with RSV diagnosis
Clinical Symptoms
 Gestational age under 37 weeks 26% (n = 12) 14% (n = 22) NS 16.43
 Age under 6 months 72% (n = 34) 85% (n = 136) <0.05 82.13
 Temperature above 38 °C 36% (n = 17) 42% (n = 67) NS 40.60
 Signs of Respiratory Distress 68% (n = 32) 89% (n = 143) <0.001 84.54
 Feeding Difficulties 32% (n = 15) 33% (n = 52) NS 32.37
Final diagnosis
 Bronchiolitis 64% (n = 30) 91% (n = 145) <0.001 84.54
 Pneumopathy 6% (n = 3) 9% (n = 15) NS 8.71
 Asthma 9% (n = 4) 3% (n = 5) NS 4.35
Patients Management
 Corticosteroids 60% (n = 28) 72% (n = 115) NS 69.08
 Antibiotics 23% (n = 11) 20% (n = 32) NS 20.77
 Aerosol Therapy 72% (n = 34) 86% (n = 138) <0.05 83.10
 Epinephrine Aerosol 53% (n = 25) 71% (n = 113) <0.05  
  1. Infants with RSV diagnosis were compared at the laboratory (Group 2: SOFIA®RSV negative and PCR RSV positive) and at point-of-care testing (POCT, Group 3: SOFIA®RSV positive)
  2. Aerosol Therapy included Epinephrine, Salbutamol, Ipratropium bromide, Budesonide or normal saline
  3. NS Non Significant. Chi2 test was used for statistical comparison