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Table 2 Summary of study time and collection of specimens and data

From: A multicentre double-blind randomised controlled trial evaluating the efficacy of daily use of antibacterial mouthwash against oropharyngeal gonorrhoea among men who have sex with men: the OMEGA (Oral Mouthwash use to Eradicate GonorrhoeA) study protocol

Week 0 3 6 9 12
Location Clinic Home Clinic Home Clinic
A. Biospecimens
 Oropharyngeal swab on both tonsillar fossae for gonorrhoea tested by NAAT     
 Oropharyngeal swab on posterior oropharynx for gonorrhoea tested by NAAT     
 Oropharyngeal swab on both tonsillar fossae for gonorrhoea tested by culture     
 Oropharyngeal swab on posterior oropharynx for gonorrhoea tested by culture     
 Oropharyngeal swab on both tonsillar fossae for gonorrhoea and chlamydia tested by NAAT     
 Oropharyngeal swab on posterior oropharynx for gonorrhoea and chlamydia tested by NAAT     
 Saliva for gonorrhoea tested by NAAT  
 First-void urine for gonorrhoea and chlamydia tested by NAAT     
 Anorectal swab for gonorrhoea and chlamydia tested by NAAT     
 Serology for HIV and syphilisa     
B. Questionnaire data
 Demographic characteristics (e.g. age, country of birth, education level)     
 History of mouthwash use (e.g. frequency, type of mouthwash)     
 Sexual risk behaviours
 Antibiotic use
 Mouthwash adherence  
 Adverse events  
 Mouthwash acceptability/tolerability     
  1. NAAT Nucleic acid amplification test
  2. aHIV-positive men will only be tested for syphilis but not HIV