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Table 2 Baseline characteristics of smear-negative presumptive TB patients who received an Xpert® MTB/RIF by whether the clinician would have treated them without access to the Xpert result or not

From: Treatment decisions and mortality in HIV-positive presumptive smear-negative TB in the Xpert® MTB/RIF era: a cohort study

Characteristic   No pre-XP empirical diagnosis Pre-XP empirical diagnosis Missing response Total P-value
Total (n [%])   142 29 4 175  
Age (mean[SD])   40 (11) 39 (9) 47 (11) 40 (11) 0.52
Female sex (n [%])   80 (56.3) 16 (55.2) 3 (75) 99 (56.6) 0.75
CD4 count (median [IQR])*   280 (189, 483) 238 (132, 343) 403 (390, 983) 275 (179, 478) 0.66
ART at TB treatment initiation (n [%])   72 (50.7) 16 (55.2) 1 (25) 89 (50.9) 0.53
Prior TB treatment (n [%])   23 (16.2) 6 (20.7) 0 (0) 29 (16.6) 0.55
Symptomatology at presentation (n [%]) Cough 140 (98.6) 29 (100) 4 (100) 173 (98.9) 0.79
Fever 101 (71.1) 19 (65.5) 4 (100) 124 (70.9) 0.36
Night sweats 72 (50.7) 13 (44.8) 3 (75) 88 (50.3) 0.51
Weight loss 48 (33.8) 14 (48.3) 1 (25) 63 (36) 0.3
Anorexia 67 (47.2) 14 (48.3) 3 (75) 84 (48) 0.55
Chest pain 46 (32.4) 10 (34.5) 1 (25) 57 (32.6) 0.93
  1. IQR interquartile range, n number, Rx treatment, SD standard deviation, TB tuberculosis, XP Xpert MTB/RIF
  2. *On 124, 26, 2 and 152 patients, respectively