You are viewing the site in preview mode

Skip to main content

Advertisement

Table 4 Validation of optimal risk score E.a in MACS, 1984–2010

From: Development and validation of a risk score to assist screening for acute HIV-1 infection among men who have sex with men

Cutoffb Sensitivity % Specificity % Positive LR Negative LR % to be tested
≥ 0.9 85.4 53.0 1.8 0.3 47.2
≥ 1.1 67.2 72.3 2.4 0.5 27.9
≥ 1.5 56.2 88.8 5.0 0.5 11.4
≥ 1.6 51.8 89.9 5.1 0.5 10.3
≥ 1.7 48.9 90.7 5.3 0.6 9.5
≥ 1.8 48.9 90.9 5.4 0.6 9.3
≥ 2.0 48.8 91.1 5.4 0.6 9.1
≥ 2.4 28.5 97.1 9.8 0.7 3.0
  1. LR likelihood ratio, MACS Multicenter AIDS Cohort Study
  2. aIncluding 4 symptoms and 3 risk factors (Table 3, row 7): fever, lymphadenopathy, oral thrush, weight loss, gonorrhea, receptive condomless anal intercourse, >5 sexual partners
  3. bCutoff levels were defined by each possible sum of the score of symptoms and risk factors, based on the beta coefficient (Table 3, column 8)