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Table 3 Performance of CareStart™ by species identified in comparison to the standard reference light microscopy

From: Performance comparison of CareStart™ HRP2/pLDH combo rapid malaria test with light microscopy in north-western Tigray, Ethiopia: a cross-sectional study

  Pf or mixed by LM vs pf/pan by RDT Non-Pf (by LM) vs Pan only (by RDT) All positive by LM vs all positive by RDT
Sensitivity (%) (95% CI) 94.4 (94.3–94.5) 85.0 (84.8–85.2) 95.4 (95.3–96.0)
Specificity (%) (95% CI) 98.9 (98.8–99.0) 99.7 (99.5–100.0) 99.3 (99.2–99.4)
Positive predictive value (%) (95% CI) 85.0 (84.8–85.14) 89.5 (89.4–89.6) 99.6 (99.58–99.62)
Negative predictive value (%) (95% CI) 99.0 (98.9–99.04) 99.3 (99.2–99.4) 98.9 (89.8–90.0)
Agreement between tests Kappa 0.85 (0.76–0.91) 0.89 (0.78–0.93) 0.92 (0.80–0.93)
  1. Pf Plasmodium falciparum, LM light microscopy, RDT rapid diagnostic test