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Table 1 Demographic characteristic of 270 eligible participants

From: Diagnostic accuracy and usefulness of the Genotype MTBDRplus assay in diagnosing multidrug-resistant tuberculosis in Cameroon: a cross-sectional study

  All Study participants N = 270 (%) New PTB patients N = 79 (%) Previously treated PTB patients (N = 169) Patients with unknown PTB history (N = 22) a P-value
Variables
 Age (y); mean SD 37.7 ± 13.4 36.6 ± 14 38.0 ± 13.5 39.1 ± 10.7 0.271
Gender      0.667
 Male 179 (66) 50 (63) 113 (67) 16 (73)  
 Female 91 (34) 29 (37) 56 (33) 6 (27)  
Cities      <0.0001
 Bamenda 14 (5) 5 (6.3) 9 (5.3) 0 (0)  
 Douala 133 (49) 65 (82.3 47 (27.8) 21 (95.5)  
 Yaounde 123 (46) 9 (11.4) 113 (66.9 1 (4.5)  
HIV status      0.0008
 Positive 63 (23) 13 (16.5) 50 (29.6) 0 (0)  
 Negative 140 (52) 40 (50.6) 96 (56.8) 4 (18.2)  
 Unknown 67 (25) 26 (32.9) 23 (13.6) 18 (81.8)  
Smear Status      0.0012
 Smear negative 44 (16) 5 (6.3) 38 (22.5) 1 (4.5)  
 Smear positive 226 (84) 74 (93.7) 131 (77.5) 21 (95.5)  
Grading of positive smears
Smear positive (AFB Scanty) 17 (6) 5 (6.8) 10 (7.6) 2 (9.1)  
Smear positive (AFB 1+) 17 (6) 6 (8.1) 8 (6.1) 3 (13.6)  
Smear positive (AFB 2+) 46 (7) 22 (29.7) 22 (16.8) 2 (9.1)  
Smear positive (AFB 3+) 146 (54) 41 (55.4) 91 (69.5) 14 (63.6)  
Phenotypic DST results      <0.0001
 Susceptible 152 (56) 53 (67.1) 82 (48.5) 17 (77.3)  
 Mono-drug resistant 20 (7) 7 (8.9 11 (6.5) 2 (9.1)  
 Polydrug resistant 5 (2) 2 (2.5) 2 (1.2) 1 (4.5)  
 MDR 49 (18) 7 (8.9) 42 (24.9) 0 (0)  
bNone 44 (16) 10 (12.7) 32 (18.9) 2 (9.1)  
  1. Abbreviations: SD Standard deviation, PTB Pulmonary Tuberculosis, AFB Acid-Fast-Bacilli, DST Drug susceptibility testing, MDR Multidrug-resistant
  2. aThe p-value was obtained from comparison between new and previously treated TB patients individuals
  3. bNone implies no growth of Mycobacterium tuberculosis complex bacilli observed