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Table 1 Association of maternal and neonatal characteristics in patients who used or did not use ranitidine in a Brazilian NICU, 2014–2015

From: Use of ranitidine is associated with infections in newborns hospitalized in a neonatal intensive care unit: a cohort study

Variable Not exposed to Ranitidine Exposed to Ranitidine p-value
n = 185 n = 115
Maternal and prenatal care information
 Age mother, mean (SD) 25.0 (7.2) 24.5 (6.8) 0.53a
  > 6 visits prenatal care, n (%) 56 (30.3) 34 (29.6) 0.89b
 Hypertension, n (%) 16 (8.6) 13 (11.3) 0.45b
 Diabetes Mellitus, n (%) 1 (0.5) 1 (0.9) 0.73b
 Gestational diabetes, n (%) 1 (0.5) 1 (0.9) 0.73b
 Caesarean section delivery, n (%) 95 (51.4) 47 (40.9) 0.08b
Characteristics of the neonates
 Male, n (%) 88 (47.6) 60 (52.2) 0.44b
 Twins, n (%) 31 (16.8) 19 (16.5) 0.95b
 Gestational age, median (IQR) 32 (31–34) 32 (30–33) 0.26c
 Birth weight (g), median (IQR) 1474 (1163–1863) 1410 (1150–1810) 0.29c
 Apgar score at 1 min, median (IQR) 7 (5–8) 7 (5–8) 0.24c
 Apgar score at 5 min, median (IQR) 9 (8–9) 8 (8–9) 0.16c
Devices used by the neonate
 Duration of mechanical ventilation (d), mean (SD) 2.0 (3.3) 5.5 (7.2) <0.001a
 Duration of umbilical catheter (d), mean (SD) 1.9 (2.6) 2.8 (2.7) 0.007a
 Duration of central catheter peripherally inserted (d), mean (SD) 4.0 (6.0) 7.2 (8.2) <0.001a
 Duration of orogastric tube (d), mean (SD) 19.9 (15.3) 11.9 (9.3) <0.001a
 Duration of parenteral nutrition (d), mean (SD) 3.0 (4.3) 5.9 (5.4) <0.001a
  1. d days, SD standard deviation, IQR interquartile range
  2. aT-Student test
  3. bChi-Square test
  4. cMann-Whitney U test