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Table 3 Predictors for vaginal HIV RNA shedding in 150 women living with HIV, included in the study. Unadjusted and adjusted for: age at inclusion, ethnicity, plasma HIV RNA, CD4 cell count, herpes viridae DNA, HPV and bacterial vaginosis (Nugent score)

From: Bacterial vaginosis, human papilloma virus and herpes viridae do not predict vaginal HIV RNA shedding in women living with HIV in Denmark

Predictors of vaginal HIV RNAa Vaginal HIV RNA shedding positive (n = 17) Vaginal HIV RNA shedding negative (n = 133) Unadjusted odds ratios p-value Adjusted odds ratios p-value
Age at inclusion (years), n (%)
  < 40 6 (9.8) 55 (90.2) 1.00 - 1.00 -
  ≥ 40 11 (12.4) 78 (87.6) 1.29 (0.45–3.71) 0.63 1.43 (0.34–6.00) 0.63
Ethnicity, n (%)
 White 6 (11.3) 47 (88.7) 1.00 - 1.00 -
 Asian 1 (4.2) 23 (95.8) 0.34 (0.04–3.0) 0.33 0.67 (0.06–7.27) 0.74
 Black 10 (14.1) 61 (85.9) 1.28 (0.44–3.79) 0.65 1.70 (0.41–7.16) 0.47
 (missing) (0) (2)     
 Combined p-value     0.73   0.60
HIV RNA (copies/ml), n (%)
  ≥ 40 2 (9.5) 19 (90.5) 1.00 - 1.00 -
  < 40 11 (9.4) 106 (90.6) 0.99 (0.20–4.80) 0.99 1.19 (0.21–6.63) 0.85
 (missing) (4) (8)    
CD4 count (cells/μl), n (%)
  < 350 2 (9.1) 20 (90.9) 1.00 - 1.00 -
  ≥ 350 11 (9.4) 106 (90.6) 1.04 (0.21–5.04) 0.96 1.15 (0.22–6.09) 0.87
 (missing) (4) (7)    
Herpes viridae PCR positive, n (%)
 Yes 7 (13.5) 45 (86.5) 1.00 - 1.00 -
 No 9 (9.6) 85 (90.4) 0.68 (0.24–1.95) 0.47 0.83 (0.21–3.26) 0.79
 (missing) (1) (3)    
HPVb PCR positive, n (%)
 Yes 10 (14.9) 57 (85.1) 1.00 - 1.00 -
 No 6 (8.8) 62 (91.2) 0.55 (0.19–1.62) 0.23 0.73 (0.21–2.60) 0.63
 (missing) (1) (14)    
BVc by Nugent score, n (%)
 Yes 5 (10.4) 43 (89.4) 1.00 - 1.00 -
 No 12 (11.8) 90 (88.2) 1.15 (0.38–3.46) 0.81 1.80 (0.43–7.62) 0.42
  1. a The validity of the model was tested using the Hosmer and Lemeshow Goodness-of-Fit Test
  2. b HPV human papilloma virus
  3. c Bacterial vaginosis