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Table 5 Infectious outcomes of the intent to treat and per-protocol study populations stratified by ciprofloxacin susceptibility status

From: Evaluation of targeted antimicrobial prophylaxis for transrectal ultrasound guided prostate biopsy: a prospective cohort trial

  Ciprofloxacin-susceptible Ciprofloxacin-resistant All P value
Intent to Treat N (%) = 430 (84.3) N (%) = 80 (15.7) N (%) = 510  
Any infection n, (%), 95% CI 6, (1.4), 0.5–3.8 3, (3.8), 0.8–10.6 9 (1.8) 0.8–3.3 0.314
 No/Yes (n/n; %/%) 424/6 (98.6/1.4) 77/3 (96.2/3.8) 501/9 (98.2/1.8)  
 Type of infection; n (%)     0.277
  None 424 (98.6) 77 (96.2) 501 (98.2)  
  Uncomplicated UTI 3 (0.7) 2 (2.5) 5 (1.0)  
  Complicated UTI 1 (0.2) 0 (0.0) 1 (0.2)  
  Urosepsis 2 (0.5) 1 (1.3) 3 (0.6)  
Per Protocol N = 406 (83.9%) N = 78 (16.1%) N = 484  
Any infection n, (%), 95% CI 6, (1.5), 0.5–3.0 3, (3.9), 0.8–10.8) 9, (1.9), 0.9–3.5 0.337
 No/Yes (n/n; %/%) 400/6 (98.5/1.5) 75/3 (96.1/3.9) 475/9 (98.1/1.9)  
 Type of infection; n (%)     0.288
  None 400 (98.5) 75 (96.1) 475 (98.1)  
  Uncomplicated UTI 3 (0.7) 2 (2.6) 5 (1.0)  
  Complicated UTI 1 (0.2) 0 (0.0) 1 (0.2)  
  Urosepsis 2 (0.5) 1 (1.3) 3 (0.6)  
  1. Abbreviations: UTI urinary tract infection