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Table 1 Clinical and laboratory characteristics of the study group

From: Novel serum biomarkers modified by the body mass index z-score for the detection of liver fibrosis and steatosis in children with chronic hepatitis C

Characteristics Data
Number   30
Sex Male (%)/female (%) 14 (47)/16 (53)
Age at liver biopsy (years) Mean ± SD 9.4 ± 3.7
Duration of infection (years) Mean ± SD 8.2 ± 3.1
BMI z-score Mean ± SD 0.39 ± 1.04
Mode of infection Vertical (%) 22 (73)
Nosocomial (%) 7 (23)
HCV genotype (%) 1a 2 (7)
1b 19 (63)
3 5 (17)
4 4 (13)
Viral load (IU/ml) HCV median (IQR) 5.95 × 105 (2.25 × 105–1.53 × 106)
Laboratory findings Mean ± SD/median (IQR) ALT (IU/l) 60.5 (36–79)
AST (IU/l) 50 (37–68)
Platelets (× 109/l) 308.2 ± 90.5
METAVIR F 0 8 (27)
1 15 (50)
2 7 (23)
3–4 0
Steatosis Any (%) 8 (27)
  Significant (%) 4 (13)
APRI Mean ± SD 0.48 ± 0.26
FIB-4 Mean ± SD 0.22 ± 0.13
M-APRI Mean ± SD 0.28 ± 0.69
M-FIB-4 Mean ± SD 0.09 ± 0.28
B-AST Mean ± SD 31.71 ± 69.87
  1. ALT alanine aminotransferase, AST aspartate aminotransferase, BMI body mass index, APRI aspartate-to-platelet Ratio Index, FIB-4 Fibrosis-4 test, M-APRI modified aspartate-to-platelet ratio index (BMI z-score x APRI); M-FIB-4 modified Fibrosis-4 index (BMI z-score x FIB-4), B-AST BMI z-score x AST