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Table 3 Cost-effectiveness analysis of new diagnostic algorithms

From: Modeling the patient and health system impacts of alternative xpert® MTB/RIF algorithms for the diagnosis of pulmonary tuberculosis in Addis Ababa, Ethiopia

Diagnostic algorithms DALYs averted per year Additional health system costs per year over 10 years (US$) Cost-effectiveness ratio (US$ per DALY averted)
YLL YLD DALY ACER ICER
ZN-Spot-Morning-Spot 0 0 0    
FN-Spot-Morning-Spot 1935 25 1965 3456 2 Dominated
Targeted-Xpert-ZN-Negative-Spot-Morning-Spot 4660 64 4724 950669 201 Dominated
Targeted-Xpert- MDR-HIV-ZN-Spot-Morning-Spot 2838 39 2878 582813 203 Dominated
Full-Xpert 8988 128 9117 1161133 127 370.1
FN-Spot-Spot 4299 59 4358 -19748 -5 12.6
FN-Spot-Morning 1728 25 1747 -52727 -30 -30.2
Targeted-Xpert-MDR-HIV-FN-Spot-Spot 7256 104 7360 510831 69 176.7
  1. YLL years of life lost, YLD years lost due to disability, DALY disability adjusted life year. ACER average cost-effectiveness ratio, ICER incremental cost-effectiveness ratio