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Table 2 Association of Family History with Herpes Zoster with Different Characteristics

From: A case control study on family history as a risk factor for herpes zoster and associated outcomes, Beijing, China

HZ with different characteristics Family historya Odds ratio (95% confidence interval)   P value for trend test
Yes, n (%) No, n (%) P value
Controls 33 (4.9) 645 (95.1) Reference   
All HZ case-patients 24 (10.6) 203 (89.4) 2.4 (1.4–4.3) 0.002 NA
HZ with PHN 2 (18.2) 9 (81.8) 6.0 (0.5–66.2) 0.14 0.002
HZ without PHN 22 (10.2) 194 (89.8) 2.3 (1.3–4.2) 0.006  
Recurrent HZ 4 (15.4) 22 (84.6) 9.4 (1.0–88.5) 0.05 0.005
Primary HZ 20 (10.0) 181 (90.0) 2.2 (1.2–3.9) 0.01  
HZ with moderate/severe pain 21 (13.1) 139 (86.9) 3.2 (1.7–6.0) <0.001 <0.001
HZ with mild or no pain 3 (4.5) 64 (95.5) 0.8 (0.2–3.3) 0.72  
  1. HZ herpes zoster; adefined as history of HZ among first degree relatives (i.e., parents, offspring, siblings)