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Table 1 Patient characteristics and outcome

From: Hepatic tuberculosis in human immunodeficiency virus co-infected adults: a case series of South African adults

Pt Gender Clinical features Laboratory markers at time of liver biopsy Chest X-ray findings Abdominal (and other) ultrasound findings Duration of anti-TB therapy pre-liver biopsy (Days) Duration of anti-TB therapy post-liver biopsy (Months) Outcome at 1 year follow-up
   H J S CD4 cells/μl TBil μmol/l ALT u/l ALP u/l GGT u/l ALB g/l      
1 F Y N N 43 15 49 2339 1268 17 Normal ALN 7a 13 R
2 F Y Y N 55 40 56 106 194 17 Normal H, ALN 9 9 R
3 M N N N 17 7 98 1035 275 23 Extensive paratracheal and hilar shadowing, active TB, nodular shadowing Normal 140 5 D
4 F Y Y Y 6 35 32 654 547 15 Consolidation with breakdown in RUZ, cavitation Findings NR 50 7 R
5 M N N Y 175 31 110 280 194 14 Large paratracheal lymph nodes Findings NR Post-biopsy 9 R
6 F N N N 96 44 94 1110 994 16 Reticulonodular shadowing, paratracheal lymph nodes Findings NR 6 NR R
7 F Y N N 56 3 35 1088 873 15 Extensive reticulonodular shadows, miliary pattern Findings NR 21a <1 D
8 M Y N N 157 16 37 467 401 17 Left PE H, ALN 175 9 MDR-TB
9 M Y N Y 117b 14 26c 387 112 18 Diaphragm pushed up. Other findings NR H, Sp 13 NR R
10 F Y N Y 34 14 42 323 451 21 Nodular infiltrates in right lower zone H, Sp 5 9 R
11 F Y N N 123b 42 116 415 326 17 Miliary pattern Normal 0 NR R
12 F Y N N 15b 6 11 186 78 15 Findings NR H, ALN Post-biopsy 1 D
13 F Y Y N 163 21 30c 448 278 17 LUZ consolidation, opacities in RUZ, RMZ and LMZ. Hilar lymph nodes H, ALN, Sp, ascites, (PE, PCE) 39 8 D
14 F Y Y N 20 21 95 2226 1257 26 Fibrosis of right upper lobe, nodular infiltrates in both lower zones ALN 121a 9 R
15 F Y Y N 42d 24 33 541 599 24 Small bilateral PE H 219 >8 XDR-TB
16 F Y Y N 17d 65 57 1050 443 21 Right upper lobe infiltrates ALN, Sp 121a 9 R
17 F Y Y N 49 26 28 321 86 11 Bilateral opacification, miliary TB ALN, Sp 103a 6 D
18 F Y N Y 45 6 41 463 1075 20 Reticular infiltrates in RUZ and LUZ H, ALN 50 6 R
19 M Y N Y 59 32 55 297 321 20 Mediastinal widening, no infiltrates H, ALN, Sp (PE, PCE) 97 3 D
20 M Y N N 37 13 163 326 460 28 Findings NR Not done 81a >8 R
  1. Pt Patient, TB Tuberculosis, H hepatomegaly, J Jaundice, S Splenomegaly, CD4 cluster of differentiation 4, TBil Total Bilirubin, ALT alanine transaminase, ALP alkaline phosphatase, GGT gamma-glutamyltransferase, ALB albumin, F Female, M Male, Y Yes, N No, ALN Abdominal lymph node/s, aanti-TB therapy interrupted pre-biopsy due to abnormal liver enzymes, R Resolved, D Died, RUZ Right upper zone, NR not reported, PE Pleural effusion, MDR-TB Multidrug-resistant tuberculosis, bon Antiretroviral therapy, cSerology positive for Hepatitis B Surface Antigen, Sp Splenic lesions, LUZ Left upper zone, RMZ Right mid zone, LMZ Left mid zone, PCE Pericardial effusion, dART stopped 1–2 months pre-biopsy, XDR-TB Extensively drug-resistant tuberculosis