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Table 3 Prevalence of Human Papillomavirus (HPV) and its genotype distribution among normal and histo-pathological abnormal lesion

From: Epidemiologic characterization of human papillomavirus (HPV) infection in various regions of Yunnan Province of China

Variable Normal CIN1 CIN2 CIN3 SCC P-Value
(n = 16968) (n = 458) (n = 247) (n = 181) (n = 44)
overalla 10.0 (9.5–10.4) 81.2 (77.6–84.8) 86.2 (81.9–90.5) 94.5 (91.2–97.8) 95.4 0.001
High riska 9.1 (8.7–9.5) 64.0 (59.6–68.4) 65.2 (59.3–71.1) 80.1 (74.3–85.9) 88.6 (79.2–98.0) 0.001
Othersa 166 (1.0) 17.2 (13.8–20.6) 21.0 (15.9–26.1) 14.4 (9.3–19.5) 6.8 0.17
Singlea infectiona 8.3 (7.9–8.7) 56.8 (51.9–60.9) 55.5 (49.3–61.7) 72.4 (65.9–78.9) 77.3 (64.9–89.7) 0.001
Multiple infectiona 1.8 (1.6–2.0) 24.4 (20.5–28.3) 30.8 (25.1–36.5) 22.1 (16.1–28.1) 18.2 (6.8–29.6) 0.5
Unidentifieda 0.7 7.0 (4.7–9.3) 8.1 (4.7–11.5) 6.6 (3.0–10.2) 9.1 (0.6–17.6)  
HR-HPV       
 HPV-16a 2.2 (1.9–2.4) 21.0 (17.3–24.7) 16.2 (11.6–20.8) 33.1 (26.3–39.9) 45.4 (30.7–60.1) 0.001
 HPV-52a 2.3 (2.1–2.5) 20.1 (16.4–23.8) 19.4 (14.5–24.3) 11.0 (6.5–15.5) 15.9 (5.1–26.7) 0.025
 HPV-58a 1.4 13.1 (10.0–16.2) 14.6 (10.2–20.0) 19.9 (14.1–25.7) 18.2 (6.8–29.6) 0.04
 HPV-18a 0.6 5.2 (3.2–7.2) 1.6 (0.03–3.2) 17.7 (12.1–23.3) 18.2 (6.8–29.6) 0.001
 HPV-51 92 (0.5) 16 (3.5) 12 (4.8) - -  
 HPV-68 84 (0.5) 23 (5.0) 8 (3.2) 7 (3.9) -  
 HPV-33 80 (0.5) 20 (4.4) 20 (8.1) 4 (2.2) -  
 HPV-39 76 (0.4) 28 (6.1) 8 (3.2) 4 (2.2) -  
 HPV-31 48 (0.3) 6 (1.3) 4 (1.6) 5 (2.8) -  
 HPV-56 40 (0.2) 8 (1.7) 8 (3.2) 4 (2.2) -  
 HPV-59 40 (0.2) 8 (1.7) - 4 (2.2) 4 (9.1)  
 HPV-45 4 (0.02) 6 (1.3) - 2 (1.1) -  
 HPV-35 9 (0.05) 3 (0.6) - - -  
PHR-HPV       
 HPV-53 128 (0.7) 28 (6.1) 20 (8.1) - -  
 HPV-81 52 (0.3) 24 (5.2) 19 (7.7) 12 (6.6) -  
 HPV-66 44 (0.2) 8 (1.7) 8 (3.2) 4 (2.2) 3 (6.8)  
Others       
 HPV-61 24 (0.1) - 3 (1.2) - -  
 HPV-11 24 (0.1) - 4 (1.6) 4 (2.2) -  
 HPV-6 12 (0.07) - - 4 (2.2) -  
 HPV-43 8 (0.05) 4 (0.9) - 3 (1.6) -  
 HPV-44 8 (0.05) 4 (0.9) - - -  
 HPV-42 4 (0.02) 2 (0.4) - 3 (1.6) -  
 HPV-55 4 (0.02) 3 (0.6) - - -  
 HPV-40 4 (0.02) - - - -  
 HPV-67 1 (0.005) - - - -  
 HPV-69 1 (0.005) - - - -  
 HPV-70 2 (0.01) - - - -  
 HPV-71 3 (0.01) - - - -  
 HPV-82 6 (0.03) - - - -  
 HPV-83 2 (0.01) - - - -  
  1. n number, a95 % Confidence interval