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Table 1 Pregnant women population groups and model key parameters according to the observed data in the different age groups

From: Estimating mother-to-child HIV transmission rates in Cameroon in 2011: a computer simulation approach

Age groups (years) 15–49 15–19 20–24 25–29 30–34 35–39 40–44 45–49 Data source
Total number of pregnant women expected 995, 533 231, 982 202, 093 173, 223 125, 437 108, 513 80, 638 73, 647 Cameroon [18, 19]
HIV prevalence, % 5.6 2.0 3.4 7.6 7.3 10.0 7.1 6.4 Cameroon [18]
Access to Antenatal Care), % 36.5         Cameroon [19]
Prenatal HIV testing, % 29.3         Cameroon [19]
Receipt of maternal HIV test result, % 92.4         Cameroon [19]
Mortality during pregnancy, % 4         Cameroon [19]
Live birth among HIV uninfected women, % 95         Cameroon [9, 19]
Live birth among HIV infected women, %   94.6 72.7 68.9 63.3 58.4 52.0 51.9 [17, 26]
ARV prophylactic coverage for HIV infected pregnant women, % 20.3         Cameroon [19]
CD4 cell count quantification for HIV infected women, % 6.9         Cameroon [19]
Pregnant women ART eligible in ANC, % 60         Cameroon [19]
ART coverage for eligible women in ANC, % 25         Cameroon [19]
HIV MTCT rate at 6-week in the absence of MTCT, % 22         Sub-saharan Africa [23, 28]
Treatment Effectiveness Expected          [21, 23]
-Short course ARV (% reduction) 86.7         
-Long course ARV/ ART (% reduction) 93.7         
Rate of breastfeeding exposure among HIV exposed children known at birth (%) 46         Cameroon, Pediacama 1, CIRCB field studiesb
Rate of breastfeeding exposure among children not known to be HIV exposed at birth, (%) 97         Cameron [18]
Intra-partum incidence of HIV infection (per 100 woman-year of follow-up), %   2 2 1.6 1.3 1 0.6 0.6 Sub-saharan Africa [3941]
Incident HIV infections among lactating women, % 2.0         Zimbabwe [27, 31]
Proportion of children still exposed to breastfeeding (age in months), %          Cameroon [18]
[0,2[ 97.5         
[2,4[ 98.9         
[4,6[ 96.0         
[6,9[ 95.9         
[9,12[ 90.5         
[12,18[ 70.2         
[18, 24] 29.5         
Rate of exclusive breastfeeding among non HIV exposed children (age in months), %          Cameroon [18]
[0,2[ 31.2         
[2,4[ 23.0         
[4,6[ 10.6         
[6,9[ 1.9         
[9,12[ 0.8         
[12,18[ 0.7         
[18, 24] 0.0         
Rate of exclusive breastfeeding among HIV exposed children (age in months), %          Cameroon,
         Pediacama 1, CIRCB field studiesb
[0,2[ 86.6         
[2,6[ 75.9         
[6,12[ 50.4         
[12, 18] 0.0         
Proportion of HIV exposed children who received postnatal ART, % 9.2         Cameroon [19]
Rate of mother’s retention in ART treatment after delivery        Sub-saharan Africa [42]
[0,6[ 79.1       
[6,12[ 75.0       
[12, 24] 61.6       
  1. ANC antenatal care, ART antiretroviral therapy, ARV antiretroviral, MTCT mother-to-child transmission; aPediacam is a multisite cohort study started in Cameroon in November 2007 with two main objectives: to study the feasibility and effectiveness, of early antiretroviral multi-therapy offered systematically to HIV-infected infants before 7 months of age; and to evaluate the humoral response of these children to vaccines of the Expanded Program of Immunization; bUnpublished Early Infant Diagnosis of HIV data located at CIRCB