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Table 1 Susceptibility of four PPNG isolates producing TEM-220 β-lactamase and PPNG strains containing the T539C substitution in the bla TEM allele

From: Prevalence of bla TEM-220 gene in Penicillinase-producing Neisseria gonorrhoeae strains carrying Toronto/Rio plasmid in Argentina, 2002 – 2011

  MIC (μg/ml)
Antimicrobial agent aT539C TEM-220  
  bMIC50 cMIC90 Isolate 1 Isolate 2 Isolate 3 Isolate 4
Penicillin 64 128 32 64 32 64
Ampicillin 128 256 64 128 128 128
Cefuroxime 0,25 0,5 0,125 0,125 0,125 0,125
Cefixime 0,016 0,016 0,008 0,008 0,008 0,008
Ceftriaxone 0,004 0,008 0,008 0,004 0,008 0,004
Tetracycline 1 4 0,5 1 1 1
Ciprofloxacin 0,004 0,008 0,002 0,004 0,004 0,004
Azithromycin 0,25 0,25 0,25 0,25 0,25 0,25
  1. aNumber of PPNG isolates containing the T539C substitution (n = 137)
  2. bMIC50 : MIC of inhibition of 50 % of strains
  3. cMIC90: MIC of inhibition of 90 % of strains