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Table 2 Dynamics of MHC-I and MHC-II molecules in spleen lymphocytes

From: Protective immunity against acute toxoplasmosis in BALB/c mice induced by a DNA vaccine encoding Toxoplasma gondii elongation factor 1-alpha

Marker (%) Time point Groups (n = 5)
Blank PBS PVAXI PVAX-EF-1a
MHC-I Week 0 18.19 ± 2.46 17.17 ± 2.62 16.99 ± 1.38 17.29 ± 2.34
  Week 2 16.55 ± 2.15 17.13 ± 1.91 17.06 ± 2.44 24.23 ± 3.33a
  Week 4 17.64 ± 1.82 18.02 ± 1.91 17.62 ± 1.46 31.44 ± 3.54a
  Week 6 17.88 ± 1.78 17.76 ± 1.16 18.14 ± 2.30 32.96 ± 3.04a
MHC-II Week 0 3.07 ± 0.97 2.88 ± 0.37 3.31 ± 0.49 3.27 ± 0.61
  Week 2 2.99 ± 0.71 3.17 ± 0.38 3.07 ± 0.97 4.84 ± 1.86a
  Week 4 3.25 ± 0.45 3.17 ± 0.38 3.27 ± 0.59 7.52 ± 1.42a
  Week 6 3.22 ± 0.56 3.11 ± 0.73 3.24 ± 0.53 8.26 ± 1.23a
  1. Data are presented as the mean ± SD (n = 5). a represents statistically highly significant difference (p < 0.01) as compared with control groups: Blank, PBS and pVAXI