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Table 1 Evolution of laboratory parameters and discontinuation of therapy

From: Acute Hepatitis E Virus infection with coincident reactivation of Epstein-Barr virus infection in an immunosuppressed patient with rheumatoid arthritis: a case report

Parameter (Reference or limit of detection) Day after onset of illness
  8 9 12 21 40 75
AST (<40 U/l) 1920 1787 578 53 31 26
ALT(<55 U/l) 1743 1650 1021 122 27 25
yGT(<35 U/l) 265 226 221 102 35 20
ALP (42–98 U/l) 352 296 302 150 70 58
Bilirubin (<20 umol/l) 15 15 13 16   
CRP(<5 mg/l) 41 35 14 37 12 4
CMV IgG (neg) Neg      
CMV IgM (neg) Neg      
Hepatitis A IgM (neg) Neg      
HBs Antigen (neg) Neg      
HBc Ig (neg)   Pos    Neg  
HBc IgM (neg)   Pos    Neg  
HBe Ig (neg)   Neg    Neg  
HBe Antigen (neg)   Neg     
HBs Ig (neg)   Neg     
HBV DNA (<9 IU/ml)    <9    
Hepatitis C Ig (neg) Neg      
EBV VCA IgG (neg)   Pos     
EBV NA1 IgG (neg)   Pos     
EBV VCA IgM (neg)   Pos    Pos  
EBV DNA (<122 IU/ml)    566   <122 <122
Heterophile IM (neg) Neg      
HEV IgG (neg); Diapro   Pos     
HEV IgM (neg); Diapro   Pos     
HEV IgG (<1.0 index); Wantai 5.3     19.4 19.5
HEV IgM (<1.0 index); Wantai 10.4     10.6 10.6
HEV RNA (<1000 cc/ml)     8959 <1000 <1000
Stop (\) and reinitiation (/) of       
- Prednisolon therapy 8 \      / 48
- Methotrexate therapy 8 \      / 63