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Table 5 Penicillin-binding protein 2 (PBP 2) [7] and porB gene sequence cluster (A1-D) in Neisseria gonorrhoeae isolates (n = 149) cultured from 1998 to 2005 (only isolates with resistance or decreased susceptibility to cefixime in 2002–2005) in Kanagawa area, Japan

From: Emergence and evolution of internationally disseminated cephalosporin-resistant Neisseria gonorrhoeae clones from 1995 to 2005 in Japan

PBP 2 (2003–2005, n = 76a) A1 A2 A3 B1 B2 C D
X X (62) 41 9 0 4 4 2 2
+ E101D (XXIV) (1)     1    
+ A501V (XXX) (2) 2       
XXXIV XXXIV (1)     1    
+ P551L (XXXII) (2)     2    
+ P551Q (1)     1    
- XXVI (6) 6       
PBP 2 (1998–2002, n = 73b) A1 A2 A3 B1 B2 C D
X X (67) 33 3 2 1 27 1 0
+ A532V (XXXI) (1)      1   
XXXIV XXXIV (2)     2    
+ A486V (1)     1    
  1. aOne isolate possessed the non-mosaic PBP 2 XIII [7]. The porB sequence from this isolate belonged to the cluster A2
  2. bTwo isolates possessed the non-mosaic PBP 2 VII and XI [7]