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Table 3 Resistance and decreased susceptibility to cefixime (CFM) or ceftriaxone (CRO) in Neisseria gonorrhoeae isolates cultured from 1995 to 2005 in Kanagawa area, Japan

From: Emergence and evolution of internationally disseminated cephalosporin-resistant Neisseria gonorrhoeae clones from 1995 to 2005 in Japan

Year Number of isolatesa CFM-DSa,b CFM-Ra,c CRO-DSa,b
   No.a % No.a % No.a %
1995 34 (1) 1 (1) 2.9 1 (0) 2.9 0 0
1996 70 (0) 0 0 0 0 0 0
1997 88 (1) 0 0 1 (1) 1.1 0 0
1998 89 (84) 0 0 5 (5) 5.6 0 0
1999 69 (50) 2 (2) 2.9 3 (3) 4.3 0 0
2000 54 (49) 6 (5) 11.1 6 (5) 11.1 1 (1) 1.9
2001 102 (90) 10 (9) 9.8 34 (32) 33.3 17 (17) 16.7
2002 21 (21) 0 0 12 (12) 57.1 4 (4) 19.0
2003 55 (27) 5 (4) 9.1 26 (23) 47.3 16 (14) 29.1
2004 74 (34) 10 (10) 13.5 29 (24) 39.2 16 (13) 21.6
2005 34 (15) 8 (6) 23.5 10 (9) 29.4 5 (5) 14.7
  1. aNumber of isolates examined genetically is given in parentheses
  2. bMIC = 0.125 mg/L of cefixime or ceftriaxone
  3. cMIC > 0.125 mg/L of cefixime