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Table 4 Mean annual OI prevalence (per 1000) in a cohort of HIV positive individuals before and after HAART in Uganda

From: Trends in prevalence of selected opportunistic infections associated with HIV/AIDS in Uganda

  Before HAART Early HAART Late HAART  
OI 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 X 2 trend (p-value)
Cryptococcal meningitis 5.5 5.4 2.5 3.3 2.7 2.7 1.6 1.2 4.0 1.3 1.3 0.23 1.79 (0.1807)
% change - 0 −54 +32 −18 0 −41 −25 +233 −67 0 −82  
Mycobacterium tuberculosis 76.9 45.5 29.3 16.2 9.6 13.2 9.0 10.9 9.1 7.4 6.6 11.0 157.38 (<0.0001)
% change - −41 −36 −45 −41 +37 −32 +21 −16 −19 −11 +67  
Herpes zoster 13.4 13.9 11.5 9.1 7.6 10.0 5.1 5.0 3.8 3.7 3.7 3.3 13.67 (0.0002)
% change - +4 −14 −25 11 +37 −54 2 −24 −20 0 −11  
Oral candida 172.7 106.4 83.1 32.3 26.5 20.0 17.0 12.0 12.6 15.4 8.7 6.7 458.20 (<0.0001)
% change - −38.7 −20 −62 −16 −26 −10 −33 +8 −23 −37 −20  
Genital ulcer(HSV-2) 15.1 18.2 17.6 12.3 9.3 12.0 11.2 8.1 9.2 7.2 7.7 8.9 8.8 (0.0029)
% change - +21 3.3 −33 −17 +20 −8 27 +25 −20 −12.5 +43  
  1. Key: HAART = Highly active antiretroviral therapy; % = percent; HSV-2 = Herpes simplex virus type2.