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Table 1 Hematological analysis of mice treated with khat followed by Pb A infection with reference to controls (n = 8)

From: Effect of chronic khat (Catha edulis, Forsk) use on outcome of Plasmodium berghei ANKA infection in Swiss albino mice

Group WBC*103/μL RBC *106/ μL Hb (g/dL) HCT (%) MCV (FL) MCH (pg) MCHC g/dL Plt*103/ μL Lym (%)
control (−ve) 3.8 ± 0.18 8.07 ± 0.3 12.72 ± 0.47 44.32 ± 1.67 54.85 ± 0.03 15.76 ± 0.05 28.72 ± 0.13 884.25 ± 32.5 87.2 ± 1.86
100 mg/kg§ 3.52 ± 0.25 8.32 ± 0.29 12.75 ± 0.45 43.42 ± 2.06 52.06 ± 0.64 15.32 ± 0.02 29.46 ± 0.37 810 ± 45.7 80.32 ± 4.23
200 mg/kg§ 2.85 ± 0.09** 8.7 ± 0.1 12.6 ± 0.18 45.1 ± 0.79 52.9 ± 0.55 15.67 ± 0.3 29.52 ± 0.53 766.7 ± 28.5 85.2 ± 1.72
300 mg/kg§ 2.03 ± 0.49** 8.33 ± 0.15 11.66 ± 0.1* 43.02 ± 0.7 51.66 ± 0.58* 15.23 ± 0.2 29.42 ± 0.24 770 ± 17.15* 80.06 ± 2.17
Control (+ve) 6.64 ± 0.93 7.9 ± 1.02 14.14 ± 1.74 39.43 ± 5.55 47.8 ± 1.73 17.96 ± 0.9 37.34 ± 1.3 354 ± 68.73 74.92 ± 4.87
100 mg/kg + PbA§§ 5.14 ± 1.71 6.9 ± 0.72 12.05 ± 1.23 34.47 ± 4.45 48.1 ± 0.89 17.5 ± 1.02 36.2 ± 0.71 328 ± 52 76.12 ± 11.15
200 mg/kg + PbA§§ 4.57 ± 0.94 7.3 ± 0.34 13.18 ± 0.65 37.06 ± 1.62 50.5 ± 1.23 17.3 ± 1.1 34.5 ± 0.64 173 ± 37.02** 81.85 ± 7.67
300 mg/kg + PbA§§ 4.09 ± 1.87* 7.1 ± 0.81 11.86 ± 1.48* 37.13 ± 4.43 50.1 ± 0.91 18.06 ± 0.93 36.1 ± 1.02 107 ± 21.66** 77.17 ± 8.09
  1. NB: Plt = platelet, Lym = lymphocyte, *showed significant difference (P < 0.05), **(P < 0.01). Significance level of uninfected but khat treated mice §were compared with –ve control group, while khat treated mice followed by PbA infection §§were compared to + ve control group.