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Table 1 Double exponential model PK parameters for 50 kg adult patient

From: Mass campaigns with antimalarial drugs: a modelling comparison of artemether-lumefantrine and DHA-piperaquine with and without primaquine as tools for malaria control and elimination

  AM LF DHA PPQ PQ
Adult dose 80 mg 480 mg 120 mg 960 mg 15 mg
Cmax (μg/L) 114 1017 200 30 75
Cmax scaling factor 0.5 1.5 0.25 0.5 1
Decay constant A (1/day) 0.12 1.3 0.12 0.17 0.36
Decay constant B (1/day) -- 2.0 -- 41 --
V -- 1.2 -- 49 --