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Table 1 Analysis of number of patients stratifying by exacerbations

From: Effects of long-term use of macrolides in patients with non-cystic fibrosis bronchiectasis: a meta-analysis of randomized controlled trials

Exacerbations a No. of studies Events/Total Effect size Heterogeneity
Macrolide Control OR(95%CI) P value I 2 (%) P
0 8 135/277 80/267 2.81(1.85-4.26) <0.01 * 0 0.43
1 5 37/171 31/164 1.18(0.70-2.01) 0.53 17 0.31
2 3 24/147 27/142 0.83(0.46-1.52) 0.55 34 0.22
At least 3 3 34/147 60/142 0.38(0.22-0.65) 0.0004 * 0 0.45
  1. aNumber of exacerbations per patient; bThe subgroups of at least 1 exacerbations contributed to the overall estimate;* It was suggestive of statistical significance.