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Table 3 Sensitivity analysis for correlations

From: Evaluation of using composite HPV genotyping assay results to monitor human papillomavirus infection burden through simulation

  2 High-risk vaccine type* 4 Vaccine type* 14 High-risk type* 37 HPV type*
Correlations Prespecified true Composite prevalence Composite prevalence estimate§ Est. to true ratio Prespecifiedtrue composite prevalence Composite prevalence estimate§ Est. to true ratio Prespecified true composite prevalence Composite prevalence estimate§ Est. to true ratio Prespecified true composite prevalence Composite prevalence estimate§ Est. to true ratio
0 0.064 0.151 2.36 0.121 0.279 2.30 0.293 0.647 2.23 0.663 0.947 1.43
0.05 0.064 0.151 2.36 0.121 0.275 2.27 0.282 0.616 2.19 0.617 0.904 1.47
0.1 0.064 0.151 2.36 0.119 0.269 2.26 0.271 0.584 2.15 0.576 0.861 1.49
0.2 0.063 0.147 2.33 0.115 0.255 2.22 0.247 0.526 2.13 0.501 0.776 1.55
0.3 0.062 0.144 2.32 0.110 0.242 2.20 0.223 0.473 2.12 0.436 0.695 1.59
0.4 0.061 0.141 2.31 0.104 0.228 2.19 0.200 0.423 2.12 0.376 0.615 1.63
  1. *2: high-risk vaccine types (HPV 16, 18); 4: vaccine types (HPV 6, 11, 16, 18); 14: high-risk types (HPV 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, 68); 37: HPV types (HPV 6, 11, 16, 18, 26, 31, 33, 35, 39, 40, 42, 45, 51, 52, 53, 54, 55, 56, 58, 59,61, 62, 64, 66, 67, 68, 69, 70, 71, 72, 73, 81, 82, 83, 84, 89, IS39).
  2. Pre-specified type-specific prevalence: HPV 6 = 0.028, HPV11 = 0.034, HPV16 = 0.047, HPV18 = 0.019, HPV26 = 0.022, HPV31 = 0.015, HPV33 = 0.013, HPV35 = 0.023, HPV39 = 0.011, HPV40 = 0.018, HPV42 = 0.025, HPV45 = 0.020, HPV51 = 0.041, HPV52 = 0.036, HPV53 = 0.058, HPV54 = 0.038, HPV55 = 0.024, HPV56 = 0.023, HPV58 = 0.014, HPV59 = 0.030, HPV61 = 0.040, HPV62 = 0.065, HPV64 = 0.002, HPV66 = 0.034, HPV67 = 0.013, HPV68 = 0.016, HPV69 = 0.027, HPV70 = 0.020, HPV71 = 0.056, HPV72 = 0.012, HPV73 = 0.015, HPV81 = 0.027, HPV82 = 0.054, HPV83 = 0.041, HPV84 = 0.048, HPV89 = 0.047, HPVIS39 = 0.014.
  3. Pre-specified genotyping assay sensitivity = 0.95 and specificity = 0.95.
  4. §Standard deviations of prevalence estimates ≤0.008.