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Table 1 Search strategy and selection criteria for neonatal infection and bacterial resistance articles in developing countries (2000-May 2014)

From: Burden of bacterial resistance among neonatal infections in low income countries: how convincing is the epidemiological evidence?

Search strategy
For the BI search, each DC was cross-linked with search terms “Bacterial Infections” OR “Sepsis” OR “bacter*” AND “epidemiology”. For the AR search, each DC was cross-linked with “Drug resistance, bacterial” OR (“antibiotic resistance” AND “bacter*”) AND “epidemiology”. Both searches were restricted to English language articles and the BI search was restricted to the PubMed “infant” age category (birth-23 months). Both searches were also limited by excluding the keywords and MeSH terms “travel”, “candida”, “HIV infection”, “leprosy”, “tuberculosis”, “tetanus”, “malaria”, “cholera”, or “helicobacter”. The BI search was further limited by excluding the keywords “immunization”, “immunization program”, and “vaccination”.
Inclusion criteria
Infant infection search (BI) Resistance search (AR)
Information on bacterial infections including either etiology or disease burden/incidence Bacterial pathogens
Community acquired infections Community acquired infections
Methodologically sound including clear inclusion criteria Information on antibiotic resistance profile of pathogen (proportion resistance/susceptible, etc.)
Sound microbiological methods/citation of guidelines used Sound microbiological methods/citation of guidelines used
Neonatal specific information presented Information on pathogen source and/or clinical information
  Neonatal specific information presented
Exclusion criteria
Both branches
Review study or expert opinion
Outside of developing country list
Purely nosocomial infections or no possibility to extract only community acquired infections from data
Pathogen not in the restricted list, including Neisseria gonorrhoeae, Campylobacter, Helicobacter, Vibrio, Clostridium tetani, or any Mycobacteria
Obvious methodological weakness including sampling methods
Insufficient number of isolates/insufficient number of isolates for follow-up period (minimum 10 isolates per year)
Data collection done principally before 2000
Infant infection search (BI) Resistance search (AR)
Ages outside of range of interest or ages of interest non-extractable Insufficient epidemiological info on sample source/patients/no. of bacteria isolated from neonates