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Table 6 Antimicrobial susceptibility profiles of microorganisms implicated in MC-CRBSI episodes

From: Surveillance of catheter-related infections: the supplementary role of the microbiology laboratory

Antimicrobial susceptibility profile according to antimicrobial category % isolates resistant
S. epidermidis (n = 55) S. aureus (n = 16) A. baumannii complex (n = 35) E. cloacae (n = 17) P. aeruginosa (n = 14) K. pneumoniae (n = 12)
Anti-staphylococcal β-lactams (oxacillin) 96 75 - - - -
Penicillin (ampicillin) - - - - - 100
β-lactamase inhibitors (amoxicillin/clavulanic acid) - - 100 - - 33
β-lactamase inhibitors (piperacillin/tazobactam) - - - 53 36 33
Cephamycins (cefoxitin) - - - - - 17
Non-ES cephalosporins (cefuroxime) - - - 71 - 33
ES cephalosporins (cefotaxime#, ceftazidime, cefepime) - - 100 53 21 33
Carbapenems (ertapenem#, meropenem, imipenem) - - 100 18 36 0
Aminoglycosides (amikacin*, gentamicin) 80 63 86 0 14 17
Fluoroquinolones (ciprofloxacin, moxifloxacin^) 55 75 49 0 14 17
Macrolides (erythromycin) 84 75 - - - -
Linosamides (clindamycin) 76 63 - - - -
Linezolid 0 0 - - - -
Glycopeptides (teicoplanin, vancomycin) 0 0 - - - -
Tetracycline 93 63 - - - -
Glycylcycline (tigecycline) 0 0 3 12 - 17
Fusidic acid 24 0 - - - -
Rifampicin 47 19 - - - -
Polymyxins (colistin) - - 0 6 14 0
Folate pathway inhibitors (trimethoprim/ sulphamethoxazole) 78 75 - 12 - 17
Acquired resistance profiles
S 11 25 0 47 79 67
MDR 89 75 0 53 7 33
XDR 0 0 100 0 0 0
PDR 0 0 0 0 14 0
  1. ES = extended-spectrum; S = sensitive.
  2. MDR = multidrug-resistant, non-susceptible to ≥1 agent in ≥ 3 antimicrobial categories.
  3. XDR = extensively drug-resistant, non-susceptible to ≥ 1 agent in all but ≤ 2 antimicrobial categories.
  4. PDR = pandrug-resistant, non-susceptible to all antimicrobial agents tested [20].
  5. - = not applicable to the specific bacteria, #not tested (n/t) for in P. aeruginosa, *n/t for in Gram-positive bacteria,^n/t for in Gram-negative bacteria.