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Table 3 Distribution of MIC50/MIC90 values and resistance/nonsusceptibility rates per geographic region

From: Risk factors for nasopharyngeal carriage of drug-resistant Streptococcus pneumoniae: data from a nation-wide surveillance study in Greece

City/Prefecture # strains   PG CXM CTX ERY COT TET CIP
Athens.   %ns-%r 37.9–15.8 29.8–28.7 1.8–0.4 33.2–32.1 43.6–26 24.2–23.4 3.8
Attika 273 MIC50/MIC90 0.023–2 0.047–4 0.023–0.75 0.125–256 0.5–32 0.125–24 0.75–1.5
Halkida.   %ns-%r 37–15.2 23.9–21.7 1.4–0 39.1–37.7 51.8–29.2 34.8–30.4 3.8
Evia 138 MIC50/MIC90 0.023–2 0.032–3 0.023–0.75 0.125–256 0.75–32 0.19–32 0.75–2
Thessaloniki.   %ns-%r 32.8–7.4* 21.3–18 0.8–0 34.2–34.2 38–29.8 21.3–20.5 3.3
Central Macedonia 122 MIC50/MIC90 0.032–1 0.032–2 0.016–0.5 0.125–24 0.5–32 0.25–48 0.75–1.5
Ioannina.   %ns-%r 19.2*-7.7* 11.5–11.5 2.9–0 42.3–38.5 42.3–19.2 19.2–19.2 0
Epirus 26 MIC50/MIC90 0.032–1 0.047–3 0.023–0.38 0.25–96 0.5–18 0.125–24 0.5–1
Alexandroupolis.   %ns-%r 11.8*-8.8* 8.8–8.8 0–0 17.6*-17.6 35.3–2.9 14.7–11.8 11.8
Thrace 34 MIC50/MIC90 0.023–1 0.023–2 0.023–0.5 0.125–2.5 0.38–2 0.125–24 1–3
Herakleion.   %ns-%r 53.8*-25.5* 40.4–34.6 0–0 66.7*-66.7 65.4–26.9 48.1–46.2 6.1
Crete 52 MIC50/MIC90 0.12–2 0.5–6 0.12–0.75 32–256 1–32 1.5–96 0.75–1.5
Nafplio-Tripoli-Sparti.   %ns-%r 28.0*-14.0* 24.0–24.0 1.0–0.0 14.0*-14.0 30.0–20.0 21.0–21.0 2.0
Peloponnese 101 MIC50/MIC90 0.023–2 0.023–2 0.023–0.75 0.094–128 1–2 0.125–24 0.75–2
Greece in total 746 %ns-%r 34.8–14.1 25.7–23.9 1.3–0.1 33.8–33 43.8–25.2 26.3–24.8 4.0
   MIC50/MIC90 0.023–1.5 0.032–3 0.023–0.75 0.125–256 0.5–32 0.125–24 0.75–2
  1. No resistance was recorded for levo- and moxi-floxacin. Respective MIC50/90 values were 0.75–1 and 0.125–0.19 mg/L
  2. PG: penicillin. CXM: cefuroxime. CTX: ceftriaxone. ERY: erythromycin. COT: cotrimoxazole. TET: tetracycline. CIP: ciprofloxacin
  3. *flags statistically significant differences at p level of = 0.05 when compared to Attika region