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Table 1 Characteristics of the 539 included patients.

From: Empirical use of antibiotics and adjustment of empirical antibiotic therapies in a university hospital: a prospective observational study

Characteristic Number of patients (n = 539) Percentage of all patients
Males 297 55.1%
Age in years (median; range) 69 [17–100]  
   17 to 40 years 96 17.8%
   41 to 60 years 104 19.3%
   More than 60 years 339 62.9%
Ward a   
   Medicine and geriatrics 359 66.6%
   Surgery 173 32.1%
   Medical intensive care 25 4.6%
   Surgical intensive care 10 1.9%
   Neurology 4 0.7%
Main infectious disease diagnosis upon admission   
   Respiratory tract infections 169 31.4%
   Urinary tract infections, prostatitis, epididimytis 113 21.0%
   Gastrointestinal infections b 81 15.0%
   Skin and soft tissue infections 42 7.8%
   Biliary tract infections 25 4.6%
   Suspected systemic infections without identified focus c 25 4.6%
   Sepsis d 22 4.1%
   Bone and joint infections 17 3.2%
   Ear, nose and throat infections 15 2.8%
   Central nervous system infections 11 2.0%
   Neutropenic fever 10 1.9%
   Other 5 0.9%
   No infectious disease diagnosis 4 0.7%
Total number of patients with SIRS e 256 47.5%
Charlson comorbidity index [15] (mean +/-SD) 2.4 (+/- 2.3)  
McCabe index [16] - not fatal 443 82.2%
McCabe index - fatal < 5 years 64 11.9%
McCabe index - fatal < 6 months 32 5.9%
Died in hospital 31 5.8%
  1. a If patients were on more than one ward, each ward was counted separately.
  2. b Includes gastroenteritis, diverticulitis, peritonitis, enterocolitis, appendicitis, abdominal abscess, acute abdomen.
  3. c These patients did not meet the criteria of the sepsis definition.
  4. d Sepsis: defined as clinical evidence of infection, plus SIRSe.
  5. e Systemic inflammatory response syndrome (SIRS): includes two or more of the following: temperature > 38°C or < 36°C, heart rate > 90 beats per minute, leukocytes > 12,000/μL or < 4,000/μL (band forms were not routinely determined and were therefore not considered), respiratory rate > 20 per minute.