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Table 4 Case fatality in relation to predisposing factors and underlying diseases (univariate analysis)

From: Obesity and smoking are factors associated with poor prognosis in patients with bacteraemia

Predisposing factor All patients Deceased Survivors p-value RR (95% CI)
  N = 149 N = 19 N = 130   
  n (%) n (%) n (%)   
Obesitya 27 (23.7) 7 (70.0) 20 (19.2) 0.002 9.8 (2.3–41.3)
Current smoker or ex-smokerb 66 (48.5) 13 (92.9) 53 (43.4) <0.001 16.9 (2.1–133.5)
Alcohol abuse 24 (16.1) 7 (36.8) 17 (13.1) 0.008 3.9 (1.3–11.2)
Type 1 diabetes 5 (3.4) 0 (0) 5 (3.8) 1 1.0 (0.9–1.0)
Type 2 diabetes 29 (19.5) 6 (31.6) 23 (17.7) 0.153 2.1 (0.7–6.2)
COPD 8 (5.4) 4 (21.1) 4 (3.1) 0.01 8.4 (1.9–37.1)
Haematological malignancy 11 (7.4) 0 (0) 11 (8.5) 0.36 0.9 (0.9–1.0)
Solid malignancy 15 (10.1) 3 (15.8) 12 (9.2) 0.41 1.8 (0.5–7.2)
Rheumatoid arthritis 7 (4.7) 3 (15.8) 4 (3.1) 0.045 5.9 (1.2–28.8)
Liver cirrhosis 4 (2.7) 1 (5.3) 3 (2.3) 0.42 2.4 (0.2–23.8)
Cardiac diseasec 44 (29.5) 6 (31.6) 38 (29.2) 0.834 1.1 (0.4–3.2)
McCabe II or IIId 24 (16.1) 3 (15.8) 21 (16.2) 1 1.0 (0.3–3.6)
Corticosteroid treatmente 18 (12.1) 2 (10.5) 16 (12.3) 0.824 0.8 (0.2–4.0)
Chronic diseasef 117 (78.5) 18 (94.7) 99 (76.2) 0.065 5.6 (0.7–43.9)
Age over 60 years 78 (52.3) 11 (57.9) 67 (51.5) 0.604 1.3 (0.5–3.4)
Male sex 79 (53.0) 14 (73.7) 65 (50.0) 0.053 2.8 (1.0–8.2)
Nosocomial infection 30 (20.1) 1 (5.3) 29 (22.3) 0.084 0.2 (0.03–1.5)
  1. a(BMI >30), data available from 114 patients
  2. bData available from 136 patients
  3. cCoronary artery disease, valvular disease or documented heart failure
  4. dMcCabe class II or III: ultimately fatal or rapidly fatal disease
  5. eCorticosteroids used in a dose of over 5 mg per day during one month prior to the episode of bacteraemia
  6. fAt least one chronic disease