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Table 2 Interaction as determined by means of checkerboard assay

From: In vitro evaluation of antibiotics' combinations for empirical therapy of suspected methicillin resistant Staphylococcus aureussevere respiratory infections

Combination Nr of MRSA strains (%) for which combinations gave
  Synergy No interaction Antagonism
LVX + VA (n = 50) 16 (32) 34 (68) 0
LVX + TEC (n = 50) 9 (18) 41 (82) 0
CTX + VA (n = 50) 23 (46) 27 (54) 0
CTX + TEC (n = 50) 43 (86) 7 (14) 0
LVX + VA + AMK (n = 25) 5 (20) 20 (80) 0
LVX + TEC + AMK (n = 25) 10 (40) 15 (60) 0
LVX + VA + CAZ (n = 25) 15 (60) 10 (40) 0
LVX + TEC + CAZ (n = 25) 20 (80) 5 (20) 0
LVX + VA + FEP (n = 25) 10 (40) 15 (60) 0
LVX + TEC + FEP (n = 25) 10 (40) 15 (60) 0
LVX + VA + IPM (n = 25) 5 (20) 20 (80) 0
LVX + TEC + IPM (n = 25) 10 (40) 15 (60) 0
LVX + VA + TZP (n = 25) 5 (20) 20 (80) 0
LVX + TEC + TZP (n = 25) 20 (80) 5 (20) 0
  1. LVX: levofloxacin; VA: vancomycin; TEC: teicoplanin; CTX: cefotaxime; AMK: amikacin; CAZ: ceftazidime; FEP: cefepime; IPM: imipenem; TZP: piperacillin/tazobactam.