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Table 4 Multivariate analysis of factors associated with in-hospital mortality

From: Common TNF-α, IL-1β, PAI-1, uPA, CD14 and TLR4 polymorphisms are not associated with disease severity or outcome from Gram negative sepsis

  Model 1 Model 2 Model 3
Variable RR (95% CI) P value RR (95% CI) P value RR (95% CI) P value
Age, per year increment 1.02 (1.00–1.04) 0.026 -   1.02 (1.00–1.03) 0.053
Diseases severity    -   -  
   Sepsis 1.0      
   Severe sepsis 1.25 (0.65–2.39)      
   Septic shock 1.70 (0.48–6.05) 0.674     
Intensive care admission    -   -  
No 1.0      
Yes 2.50 (0.85–7.42) 0.098     
Polymicrobial infection    -    
No 1.0     1.0  
Yes 3.02 (1.58–7.41) 0.001    2.52 (1.27–5.01) 0.008
Hemoglobin, per μmol/L increase -   0.71 (0.52–0.97) 0.031 0.70 (0.56–0.88) 0.002
Leukocyte count, per 10 9 /mL increase -   1.00 (0.96–1.05) 0.795 -  
C-reactive protein, per milligram/L increase -   1.00 (0.99–1.00) 0.287 -  
Urea, per μmol/L increase -   1.02 (0.98–1.06) 0.234 -  
Alanine transferase, per unit/L increase -   0.99 (0.98–1.00) 0.195 -  
  1. RR: relative risk; CI: confidence interval