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Table 3 In-hospital mortality according to genotype

From: Common TNF-α, IL-1β, PAI-1, uPA, CD14 and TLR4 polymorphisms are not associated with disease severity or outcome from Gram negative sepsis

Genotype In-hospital mortality (%) P value
TNF-α (G-308A)   
GG 34/182 (19)  
GA 20/106 (19)  
AA 6/16 (38) 0.19
Il-1β (C3953T)   
CC 32/178 (18)  
CT 25/117 (21)  
TT 5/22 (23) 0.61
PAI-1 (4G/5G)   
4G-4G 15/90 (17)  
4G-5G 37/183 (20)  
5G-5G 11/44 (25) 0.61
uPA (C422T)   
CC 40/187 (21)  
CT 20/114 (18)  
TT 2/12 (17) 0.86
TLR4 (A 896G)   
AA 49/274 (18)  
AG 8/27 (30)  
GG - 0.11
CD14 (C-159T)   
CC 18/92 (20)  
CT 33/156 (21)  
TT 11/66 (17) 0.90
  1. TNF-α: tumor necrosis factor alpha; Il-1β: interleukin-1 beta; PAI-1: plasminogen activator inhibitor 1; uPA: urokinase-type plasminogen activator; TLR4: toll-like receptor 4; CD14: cluster of differentiation 14; A: adenine; T: thymidine; C: cytosine; G: guanine